手术切除联合博来霉素治疗耳廓瘢痕疙瘩的疗效研究  

Effect of Surgical Resection Combined with Bleomycin on Auricular Keloid

作　　者：王宏伟[1] 陈刚[1] 李玄 WANG Hong-wei;CHEN Gang;LI Xuan(Department of Burn Plastic Surgery,Naval Hospital of PLA Eastern Theater Command,Zhoushan 316000,Zhejiang,China;Department of Anesthesiology,Naval Hospital of PLA Eastern Theater Command,Zhoushan 316000,Zhejiang,China)

机构地区：[1]中国人民解放军东部战区海军医院烧伤整形科,浙江舟山316000 [2]中国人民解放军东部战区海军医院麻醉科,浙江舟山316000

出　　处：《中国美容医学》2020年第1期8-11,共4页Chinese Journal of Aesthetic Medicine

摘　　要：目的:探究手术切除联合博来霉素对耳廓瘢痕疙瘩的治疗效果。方法:选取笔者医院2015年1月-2019年1月收治的耳廓瘢痕疙瘩患者80例,随机分为对照组和研究组,各40例,对照组进行单纯的手术切除治疗,研究组采用手术切除联合博来霉素注射治疗。评估两组疗效,比较两组患者治疗前后VSS评分以及术后复发、感染等情况。结果:研究组治疗有效率为82.50%显著高于对照组(60.00%),差异有统计学意义(P<0.05)。治疗后,两组VSS评分均显著降低,且术后1个月和3个月,研究组VSS评分均显著低于对照组,差异有统计学意义(P<0.05)。研究组复发率为5.00%显著低于对照组的22.50%,差异有统计学意义(P<0.05)。研究组感染率为2.50%,对照组为10.00%,组间比较差异无统计学意义(P>0.05)。结论:手术切除联合博来霉素注射治疗对耳廓瘢痕疙瘩有着更好的治疗效果,能够减少术后复发,值得在临床中推广应用。Objective To explore the effect of operation combined with bleomycin on the treatment of auricular keloid,VSS score and recurrence.Methods 80 patients with auricular keloid admitted to our hospital from January 2015 to January 2019 were randomly divided into the control group and the study group,40 cases in each group.The control group was treated with surgical excision alone,while the study group was treated with surgical excision combined with bleomycin injection.The curative effect,VSS score before and after treatment,postoperative recurrence and infection were compared between the two groups.Results The effective rate of the study group was 82.50%,which was significantly higher than that of the control group (60.00%),the differences was statistically significant(P<0.05).After treatment,the VSS scores of the two groups were significantly lower,and the VSS scores of the study group were significantly lower than that of the control group at 1 and 3 months after operation(P<0.05).The recurrence rate of the study group was 5.00%,which was significantly lower than that of the control group (22.50%,P<0.05).There was no significant difference in infection rate between the two groups(P>0.05).Conclusion Surgical excision combined with bleomycin injection has a better therapeutic effect on keloid of auricle and can reduce the recurrence of patients after operation.The combined therapy is worth popularizing and applying in clinic.

关 键 词：瘢痕疙瘩 耳廓 手术切除 博来霉素 复发 注射治疗 

分 类 号：R619.6[医药卫生—外科学]