具有抗病毒作用的海洋中药研究进展  

Research progress on marine Chinese materia medica with antiviral effect

作　　者：陈玫伶 郝二伟 杜正彩[1,3,4] 李聪 谢金玲[1,3,4] 赵媛媛 侯小涛 邓家刚[1,3,4] CHEN Mei-ling;HAO Ee-wei;DU Zheng-cai;LI Cong;XIE Jin-ling;ZHAO Yuan-yuan;HOU Xiao-tao;DENG Jia-gang(Guangxi Key Laboratory of Efficacy Study on Chinese Materia Medica,Nanning 530200,China;School of Pharmacy,Guangxi University of Chinese Medicine,Nanning 530200,China;Guangxi Collaborative Innovation Center of Functional Ingredients Study of Agricultural Residues,Nanning 530200,China;Guangxi Scientific Experimental Center of Traditional Chinese Medicine,Guangxi University of Chinese Medicine,Nanning 530200,China)

机构地区：[1]广西中药药效研究重点实验室,广西南宁530200 [2]广西中医药大学药学院,广西南宁530200 [3]广西农作物废弃物功能成分研究协同创新中心,广西南宁530200 [4]广西中医药大学广西中医药科学实验中心,广西南宁530200

出　　处：《中草药》2019年第23期5653-5660,共8页Chinese Traditional and Herbal Drugs

基　　金：广西科技计划基地和人才专项“广西中药药效研究重点实验室建设”项目（17-259-20）;广西科技计划项目（桂科合15104001-11）;广西科技计划项目（桂科AD17195025）;广西中医药大学2019年研究生区级创新科研项目（YCSW2019169）

摘　　要：病毒感染引起的病毒性疾病具有致病性强、发病率高、易产生耐药性等特点。目前临床多采用化学药对抗病毒性疾病,但化学药治疗效果不显著且多具有毒副作用,易对患者造成二次伤害。中药有效成分的复杂性使其可多层次、多靶点发挥抗病毒作用,而海洋中药物种丰富多样,已有研究证明海洋中药存在较好的抗病毒效果且毒副作用低,因此海洋中药抗病毒的研发和应用将在未来引起更多关注,具有广阔的市场前景。从《海洋中药学》收录的250种海洋中药中进行筛选,对具有抗病毒作用的海洋中药进行综述,以期对海洋中药抗病毒基础与临床研究提供一定借鉴。Viral diseases caused by virus infection have the characteristics of strong pathogenicity,high incidence of disease and easy to produce drug resistance.At present,chemical drugs are commonly used in clinical treatment to fight viral diseases,but the therapeutic effect of chemical drugs is not significant and most of them have toxic and side effects,which are easy to cause secondary injury to patients.The complexity of the active ingredients of Chinese materia medica makes it play an antiviral role at multiple levels and targets.Marine traditional medicine species are rich and diverse,it has been suggested that they have good antiviral effect and low side effects.The development and application of marine Chinese materia medica with anti-virus effect will attract more attention in the future,and has a broad market prospect.In this paper,250 kinds of marine Chinese materia medica with antiviral effect recorded in the book"Marine traditional Chinese medicine"were reviewed,hoping to provide some reference for the basic and clinical research of marine Chinese materia medica with antiviral effect.

关 键 词：海洋中药 抗病毒 露兜树 白骨壤 老鼠簕 

分 类 号：R285[医药卫生—中药学]