药食干预痰湿体质高血压前期疗效评价  

Evaluation of Therapeutic Effect of Herbal Intervention on Phlegm-Dampness Constitution in Pre-Hypertension Population

作　　者：刘绛云[1] 周经钲 王永生 仲海红 曹晓娟 黄玥 赵帅 关仁杰 陈炯华[1] LIU Jiangyun;ZHOU Jingzheng;WANG Yongsheng;ZHONG Haihong;CAO Xiaojuan;HUANG Yue;ZHAO Shuai;GUAN Renjie;CHEN Jionghua(The Affiliated Hospital of Integrated Traditional Chinese and Western Medicine of Nanjing University of Chinese Medicine,Jiangsu Institute of Traditional Chinese Medicine,Nanjing 210028,Jiangsu,China;Haikou School of Traditional Chinese Medicine,Haikou 570208,Hainan,China;The Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210023,Jiangsu,China;Nanjing University of Chinese Medicine,Nanjing 210023,Jiangsu,China)

机构地区：[1]南京中医药大学附属中西医结合医院/江苏省中医药研究院,江苏南京210028 [2]海南省海口市中医药学校,海南海口570208 [3]南京中医药大学附属医院,江苏南京210023 [4]南京中医药大学,江苏南京210023

出　　处：《实用中医内科杂志》2019年第11期66-69,共4页Journal of Practical Traditional Chinese Internal Medicine

基　　金：江苏省中医药局科技项目(YB2015041);第二批江苏省名老中医药专家传承工作室建设项目(苏中医科教[2016]6)

摘　　要：[目的]探讨中医辨体"药食干预"方对高血压前期痰湿体质人群的干预效果,并进行研究。[方法]入选120例痰湿体质高血压前期患者,随机分为对照组、试验一组(个体化健康管理)、试验二组(个体化健康管理+辨体药食干预方),每组40例,对治疗后各组血压监测情况、体质量表评分及安全性指标进行分析。[结果]血压监测情况:试验一组收缩压水平较对照组在第八周开始差异具有统计学意义(P <0.05),并至随访结束时差异进一步扩大;而舒张压水平差异在第八周末开始直至随访期结束具有统计学意义(P <0.05)。试验二组收缩压水平较对照组在第六周开始至第十二周末差异具有统计学意义(P <0.05),且差异逐步加大;而舒张压水平差异同样在第六周末开始直至随访期结束具有统计学意义(P <0.05)。试验一组与试验二组在十二周前,收缩压、舒展压差异未见统计学意义(P>0.05),但在第十二周差异存在统计学差异(P <0.05)。体质量表评分及安全性指标:试验一组体质量表评分在第十二周较试验前略下降,但差异无统计学意义(P> 0.05);试验二组体质量表评分在第十二周明显下降,较试验前、试验一组、对照组同期差异均具有统计学意义(P <0.05)。安全性指标方面,试验前后、组间比较差异均无统计学意义(P>0.05)。[结论]个体化健康管理及中医辨体"药食干预"对高血压前期痰湿体质人群的干预是有效、安全的。[Objective]To investigate the effect of TCM medication and food intervention on patients with pre-hypertension. [Methods]A total of 120 patients with pre-hypertension of phlegm-dampness were randomly divided into control group,experimental group 1( individualized health management) and experimental group 2( individualized health management + TCM medication and food intervention),40 cases in each group The blood pressure monitoring,body mass score and safety indicators of each group after treatment were analyzed. [Results]Blood pressure monitoring: The difference of the systolic blood pressure level between the experiment group 1 and the control group at the eighth week was statistically significant(P<0.05),and the difference was further expanded at the end of the follow-up. The difference in diastolic blood pressure level began at the eighth weekend. It was statistically significant(P<0.05) until the end of the follow-up period. The systolic blood pressure level of the experiment group 2 was statistically significant(P<0.05) from the beginning of the sixth week to the twelfth week compared with that of the control group,and the difference gradually increased. Te difference of diastolic blood pressure level also started from the sixth weekend to the follow-up period(P <0.05). There was no significant difference in systolic ordiastolic pressure between the experimental group 1 and 2 before 12 weeks(P>0.05),but there was a statistically significant difference at the 12 th week(P <0.05). Body mass scale score and safety index: The body mass scale score of the experiment group 1 decreased slightly in the twelfth week. But the difference was not statistically significant(P>0.05). The body mass scale score of the experiment group 2 mass scale score was obviously decreased in the twelfth week. There was significant difference compared with that before treatment,or that of the experiment group 1 or control group(P<0.05). In terms of safety indicators,there was no significant difference among the groups(P>0.05). [Conclusio

关 键 词：高血压前期 痰湿体质 药食干预 疗效评价 

分 类 号：R259[医药卫生—中西医结合]