对HIV感染的女性在孕前启动艾滋病抗病毒治疗后艾滋病母婴阻断的效果研究  

Effect of AIDS maternal and infant block on HIV infected women with antiviral treatment of AIDS before pregnancy

作　　者：蒲晓斌 Pu Xiaobin(AIDS Antiviral Treatment Center,the People's Hospital of Qitai County,Xinjiang Qitai 831800)

机构地区：[1]奇台县人民医院艾滋病抗病毒治疗中心

出　　处：《中国社区医师》2020年第2期59-59,61,共2页Chinese Community Doctors

摘　　要：目的:研究人类免疫缺陷病毒(HIV)感染的女性在孕前启动艾滋病抗病毒治疗后艾滋病母婴阻断的效果。方法:2016年5月-2018年5月收治HIV感染女性患者60例,将孕前确诊并启动抗病毒治疗30例设为A组,将28周后至临产时确诊并治疗30例设为B组。比较两组临床疗效。结果:A组治疗后新生儿HIV感染率显著低于B组,低体重新生儿显著高于B组,差异均有统计学意义(P<0.05)。结论:及时发现HIV感染并尽早进行抗病毒治疗,可有效阻断HIV母婴传播,降低新生儿HIV感染率。Objective:To explore the effect of AIDS maternal and infant block on HIV infected women with antiviral treatment of AIDS before pregnancy.Methods:From May 2016 to May 2018,60 HIV infected women were selected.30 cases treated with antiviral therapy before pregnancy were selected as group A.30 patients who were diagnosed and treated from 28 weeks to labor were selected as group B.We compared the clinical efficacy of the two groups.Results:After treatment,the HIV infection rate in group A was significantly lower than that in group B;low birth weight newborns were significantly higher than those in group B;the differences were statistically significant(P<0.05).Conclusion:Timely detection of HIV infection and early antiviral treatment can effectively block mother to child transmission of HIV and reduce the rate of neonatal HIV infection.

关 键 词：HIV 孕前 抗病毒治疗 母婴阻断 

分 类 号：R512.91[医药卫生—内科学]