早发型和晚发型重度子痫前期对母婴预后的影响  

Influence of early and late onset of severe preeclampsia on maternal and infant prognosis

作　　者：吴晓爽[1] 文英[2] WU Xiao-shuang;WEN Ying(The Fifth Obstetric Ward,Dalian Maternal and Child Health Hospital and Dalian Maternity Hospital,Liaoning Province,Dalian 116600,China;Maternity Ward,Dalian Maternal and Child Health Hospital and Dalian Maternity Hospital,Liaoning Province,Dalian 116600,China)

机构地区：[1]大连市妇幼保健院暨大连市妇产医院产五病房,辽宁大连116600 [2]大连市妇幼保健院暨大连市妇产医院产房,辽宁大连116600

出　　处：《中国当代医药》2020年第2期139-141,共3页China Modern Medicine

摘　　要：目的探讨早发型和晚发型重度子痫前期对母婴预后的影响。方法选取2016年6月~2018年6月我院收治的156例重度子痫前期患者作为研究对象,根据患者的发病孕龄将其分为早发型组(早发型重度子痫前期,59例)和晚发型组(晚发型重度子痫前期,97例)。收集患者的血压水平、终止妊娠时间、治疗时间、结束分娩方式等临床资料,比较两组的并发症发生情况和围生儿结局。结果早发型组的舒张压和收缩压水平均高于晚发型组,终止妊娠时间短于晚发型组,治疗时间长于晚发型组,结束分娩方式劣于晚发型组,差异有统计学意义(P<0.05)。早发型组的子痫、肝肾功能损伤、低蛋白血症以及胎盘早剥发生率均高于晚发型组,差异有统计学意义(P<0.05)。早发型组的胎儿生长受限、早产儿、低出生体重儿、胎儿窒息以及围生儿死亡率均高于晚发型组,差异有统计学意义(P<0.05)。结论与晚发型重度子痫前期患者比较,早发型重度子痫前期患者的发病孕龄早,并发症发生率高,围生儿结局差,病情也更为严重。因此,临床应加强孕期血压的监测,做到早预防、早发现、早干预,以改善母婴预后。Objective To investigate the influence of early and late onset of severe preeclampsia on maternal and infant prognosis.Methods A total of 156 patients with severe preeclampsia admitted to our hospital from June 2016 to June 2018 were enrolled as subjects,they were divided into early onset group(early onset severe preeclampsia,59 cases)and late onset group(late onset of severe preeclampsia,97 cases)according to their gestational age.Clinical data such as blood pressure level,duration of termination,treatment time,and the way of ending the delivery were collected,the incidence of complications and perinatal outcomes were compared between the two groups.Results The diastolic blood pressure and systolic blood pressure of the early onset group were higher than those of the late onset group,the duration of termination was shorter than that of the late onset group,the treatment time in the early onset group was longer than that of the late onset group,the way of ending the delivery was worse than that of the late onset group,the rate of therapeutic induction of labor was higher than that of the late onset group,the differences were statistically significant(P<0.05).The incidence rates of complications such as eclampsia,liver and kidney function injury,hypoproteinemia and placental abruption in the early onset group were higher than those in the late onset group,and the differences were statistically significant(P<0.05).In the early onset group,the incidence of fetal growth restriction,premature delivery,low birth weight,fetal asphyxia,and perinatal mortality were higher than those of the late onset group,the differences were statistically significant(P<0.05).Conclusion Compared with patients with late onset severe preeclampsia,patients with early onset severe preeclampsia have an early gestational age,a high incidence of complications,a poor perinatal outcome and a more serious condition.Therefore,clinical should strengthen the monitoring of blood pressure in pregnancy,to achieve early prevention,early detection,early i

关 键 词：重度子痫前期 早发型 晚发型 妊娠并发症 母婴预后 

分 类 号：R714.7[医药卫生—妇产科学]