乳腺实质背景强化与乳腺良恶性病变的相关性研究  

Ralationship between background parenchymal enhancement and breast benign or malignant lesions

作　　者：李小海[1] 曾宪春[1] 徐珂[1] 王荣品[1] 王楠竹[1] Li Xiaohai;Zeng Xianchun;Xu Ke;Wang Rongpin;Wang Nanzhu(Department of Radiology,Guizhou Provincial People's Hospital,Key Laboratory of Intelligent Medical Imaging Analysis and Accurate Diagnosis of Guizhou Province,Guiyang Guizhou 550002,China)

机构地区：[1]贵州省人民医院放射科暨贵州省智能医学影像分析与精准诊断重点实验室

出　　处：《遵义医科大学学报》2019年第6期673-677,共5页Journal of Zunyi Medical University

摘　　要：目的探讨乳腺良、恶性病变与乳腺实质背景强化(BPE)是否具有相关性。方法回顾性分析因乳腺病变行乳腺MRI扫描患者510例,包括绝经期164例(A组)和非绝经期346例(B组)。根据乳腺影像报告和数据系统(BI-RADS)第5版标准对BPE进行定性评价(极少强化、轻度强化、中度强化、显著强化)。经病理证实后将乳腺病变归为良性和恶性两类。采用Spearman秩相关分析乳腺良、恶性病变与BPE分型是否具有相关性。利用Fisher’s检验评估乳腺良、恶性病变的BPE分型是否具有差异性。结果乳腺良性病变中极少和轻度强化占54.8%(14.6%,40/274和40.2%,110/274),中度和显著强化占45.2%(33.2%,91/274和12.0%,33/274);恶性病变中极少和轻度强化占72.0%(31.8%,75/236和40.2%,95/236),中度和显著强化占28.0%(21.6%,51/236和6.4%,15/236)。乳腺良、恶性病变的BPE分型差异有统计学意义(P=27.135,P<0.001),Spearman秩相关分析显示具有低度负相关(r=-0.228,P<0.001)。A组乳腺良、恶性病变的BPE分型差异有统计学意义(P=13.299,P<0.05),Spearman秩相关分析显示具有低度负相关(r=-0.274,P<0.001);B组乳腺良、恶性病变的BPE分型差异无统计学意义(P=2.232,P>0.05),Spearman秩相关分析显示无相关性(r=-0.078,P=0.146);BPE极少和轻度强化在A组良性与恶性病变分别占77.0%(34.4%,21/61和42.6%,26/61)、92.2%(60.2%,62/103和32.0%,33/103),中度和显著强化所占比例较低,分别占23.0%(16.4%,10/61和6.6%,4/61)、7.8%(6.8%,7/103和1.0%,1/103)。结论乳腺恶性病变的BPE强化类型更有可能为极少和轻度强化;BPE强化类型与绝经与否密切相关。Objective To investigate whether background parenchymal enhancement(BPE)and breast benign or malignant lesions would correlate.Methods Retrospective analysis 510 patients underwent both bilateral breast MRI scan with contrast enhancement,including 164 post-menopausal and 346 pre-menopausal.According to the BI-RADS Fifth Edition,radiologists evaluated MR images classifying normal BPE as minimal,mild,moderate or marked.Breast lesions were subdivided into 2 categories based on pathology.The statistical analysis between BPE type and breast benign or malignant lesions was performed by Spearman correlation analysis.The Fisher’s test was applied to search for any statistically significant difference between BPE categorization and breast benign or malignant lesions.Results Among breast benign lesions,54.8%(14.6%,40/274 and 40.2%,110/274)showed minimal and mild BPE,while 45.2%(33.2%,91/274 and 12.0%,33/274)showed moderate and marked BPE.A significantly higher prevalence of minimal and mild BPE was found among the Breast malignant lesions,about 72.0%(31.8%,75/236 and 40.2%,95/236),while the moderate and marked BPE was minority,about 28.0%(21.6%,51/236 and 6.4%,15/236).There were statistically significant difference of Breast benign or malignant lesions and BPE categorization(P=27.135,P<0.001),Spearman correlation analysis indicated low negative correlation(r=-0.228,P<0.001).There were statistically significant difference of BPE categorization in Breast benign and malignant lesions in group A(P=13.299,P<0.05),Spearman correlation analysis indicated low negative correlation(r=-0.274,P<0.001).While in group B did not show a statistically significant difference(P=2.232,P>0.05),Spearman correlation analysis indicated no correlation(r=-0.078,P=0.146).The minimal and mild BPE in group A account for 77.0%(34.4%,21/61 and 42.6%,26/61),92.2%(60.2%,62/103 and 32.0%,33/103),respectively.While the moderate and marked BPE in group A was minority,account for 23.0%(16.4%,10/61 and 6.6%,4/61),7.8%(6.8%,7/103 and 1.0%,1/103).Conclusion Br

关 键 词：乳腺 实质背景强化 良恶性 MRI 

分 类 号：R655.8[医药卫生—外科学]