大黄的化学成分和药理研究进展  

Research Progress on Chemical Constituents and Pharmacology of Rhubarb

作　　者：金丽霞 金丽军[3] 栾仲秋 刘聪[2] 潘超[4] JIN Lixia;JIN Lijun;LUAN Zhongqiu;LIU Cong;PAN Chao(Heilongjiang Academy of Chinese Medical Sciences,Harbin 150036,China;The First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin 150040,China;Mudanjiang Tumor Hospital,Mudanjiang 157000,China;Heilongjiang University of Chinese Medicine,Harbin 150040,China)

机构地区：[1]黑龙江省中医药科学院,黑龙江哈尔滨150036 [2]黑龙江中医药大学附属第一医院,黑龙江哈尔滨150040 [3]牡丹江市肿瘤医院,黑龙江牡丹江157000 [4]黑龙江中医药大学,黑龙江哈尔滨150040

出　　处：《中医药信息》2020年第1期121-126,共6页Information on Traditional Chinese Medicine

基　　金：黑龙江省自然科学基金面上项目(H2016066);黑龙江省中医药学会青年中医药科技创新项目(ZHY19-023)

摘　　要：大黄含有多种有效成分,具有广泛的药理作用,具有泻下攻积、凉血解毒、清热泻火、逐瘀通经和利湿退黄等功效。综述近年来大黄研究的最新文献,发现大黄含有蒽衍生物类、有机酸类、挥发油类、苷类化合物和鞣质类等多种有效成分,能改善消化系统、调节血液系统、促进新陈代谢、影响神经系统,还可以改善肾脏功能、减轻延缓疼痛、抗炎、抗肿瘤、抑制细菌、抗氧化应激、抗病毒和防止肺部疾病等。Rhubarb contains many kinds of effective ingredients,which have a wide range of pharmacological effects,such as purgative and attacking accumulation,cooling blood and resolving toxins,clearing away heat and fire,removing blood stasis and activating channels,and promoting diuresis and eliminating jaundice.It is found that rhubarb contains anthracene derivatives,organic acids,volatile oils,glycosides,tannins and other effective ingredients,which can improve the digestive system,regulate the blood system,promote metabolism,affect the nervous system,improve renal function and alleviate pain.The chemical constituents of rhubarb also have the actions of anti-inflammation,anti-tumor,and anti-oxidation,as well as inhibiting bacteria,resisting virus and preventing lung diseases.

关 键 词：大黄 化学成分 药理作用 综述 

分 类 号：R284[医药卫生—中药学] R285[医药卫生—中医学]