以黄疸为首发症状的艾滋病并卡波西肉瘤1例并文献复习  

AIDS-associated Kaposi’s sarcoma with jaundice as the first symptom:a case and literature review

作　　者：吕茹 胡志亮[1] 孙丙虎[1] 魏洪霞[1] LYU Ru;HU Zhiliang;SUN Binghu;WEI Hongxia(Department of Infectious Diseases,The Second Hospital of Nanjing,Nanjing,Jiangsu 210000,China)

机构地区：[1]南京市第二医院感染病科

出　　处：《安徽医药》2020年第2期256-258,I0002,共4页Anhui Medical and Pharmaceutical Journal

基　　金：江苏省“十三五科教强卫工程”青年医学人才项目(QNRC2016059);南京卫生科技发展专项资金项目(YKK18153)

摘　　要：目的总结艾滋病并卡波西肉瘤以黄疸为首发者的的诊治经验。方法回顾性分析南京市第二医院感染病科2017年收治的1例以黄疸为首发症状的艾滋病并卡波西肉瘤病人的临床资料,并复习相关文献资料。结果病人黄疸1周入院,经抗感染、保肝降酶、退黄等对症治疗,黄疸仍迅速升高,且合并高热、咯血、呼吸衰竭,病情危重,皮肤紫蓝色结节活检提示卡波西肉瘤,经综合分析,考虑肿瘤累及肺、胆总管可能,予化疗后,黄疸降至正常,总体病情明显改善。结论卡波西肉瘤进展迅速,可累及多脏器,需及时病理诊断,黄疸可为其临床表现,治疗应以化疗为主。Objective To summarize the experience of diagnosis and treatment of AIDS-associated Kaposi’s sarcoma with jaundice as the first symptom.Methods The clinical data of a case of AIDS-associated Kaposi’s sarcoma with jaundice as the first symptom in Department of Infectious Diseases,The Second Hospital of Nanjing in 2017 were retrospective analyzed,and the relevant literature were reviewed.Results The patient was admitted to hospital for 1 week with jaundice,with treatment of anti-infection,liver protection and enzyme reduction,and jaundice reduction,Jaundice is still rising,and he was complicated with high fever,hemoptysis,respiratory failure,and endangering life.Biopsy of purple-blue nodules of skin suggests Kaposi’s sarcoma,after comprehensive analysis,the tumor was considered to involve the lung and common bile duct,after chemotherapy,jaundice was reduced to normal and the condition was obviously improved.Conclusion Kaposi’s sarcoma progresses rapidly,involving multiple organs,timely pathological diagnosis is important.Jaundice may be its clinical manifestation,and chemotherapy should be the main treatment.

关 键 词：获得性免疫缺陷综合征/并发症 肉瘤 卡波西 黄疸 阻塞性 文献复习 

分 类 号：R512.91[医药卫生—内科学] R739.5[医药卫生—临床医学]