艾拉莫德联合昆仙胶囊治疗难治性狼疮性肾炎一例  

Iguratimod combined with Kunxian capsule in treatment of refractory lupus nephritis: a case report

作　　者：何伟珍 张会昌 莫入 李培虎 戴莉萍 He Weizhen;Zhang Huichang;Mo Ru;Li Peihu;Dai Liping(Depatment of Rheumatology and Immunology,Shenzhen Futian Hospital for Rheumatic Diseases,Shenzhen 518040,China)

机构地区：[1]深圳市福田区风湿病专科医院风湿免疫科

出　　处：《新医学》2020年第1期71-73,共3页Journal of New Medicine

摘　　要：尽管狼疮性肾炎患者的治疗取得了显著进步,但仍有相当一部分患者对一线免疫抑制药物无反应,或在达到初始缓解后复发。该文报道一例对一线治疗包括环磷酰胺、吗替麦考酚酯和他克莫司等没有或部分反应的难治性狼疮肾炎患者,经艾拉莫德与昆仙胶囊联合治疗半年,尿蛋白转阴,血压恢复正常。该例提示当常规的治疗方案对狼疮肾炎无效时,如患者知情同意,可另辟途径,艾拉莫德联合昆仙胶囊是另一种可供选择的治疗方案。Despite significant advances in the management of patients with lupus nephritis, a large proportion of patients either do not respond to the first-line immunosuppressive drugs, or relapse after having achieved initial remission. In this article, we reported one case of refractory lupus nephritis who had no or partial response to the first-line therapies consisting of cyclophosphamide, mycophenolate mofetil and tacrolimus. The proteinuria was not detected and blood pressure returned to normal after 6-month treatment with iguratimod and Kunxian capsule. This case prompts that when the conventional treatment regimen is ineffective for lupus nephritis, another approach can be taken if the informed consents are obtained from the patients. Iguratimod combined with Kunxian capsule can be applied to treat lupus nephritis.

关 键 词：系统性红斑狼疮 狼疮肾炎 艾拉莫德 昆仙胶囊 

分 类 号：R593.242[医药卫生—内科学]