18F-FDG PET/CT在活动性风湿性疾病中的应用  

Clinical application of 18F-FDG PET/CT in patients with active rheumatic disease

作　　者：陆东燕[1] 丁恩慈[1] 沈婕[1] LU Dongyan;DING Enci;SHEN Jie(Department of Nuclear Medicine,Tianjin First Central Hospital,Tianjin 300192,China)

机构地区：[1]天津市第一中心医院核医学科

出　　处：《国际医学放射学杂志》2020年第1期87-92,共6页International Journal of Medical Radiology

摘　　要：风湿性疾病(RD)是一组可以累及多系统的全身性疾病,其病理改变以血管和结缔组织慢性炎症为基础。18F-FDG PET/CT可以通过半定量分析从分子水平提供功能和代谢信息,反映活动性RD的炎症程度及受累范围,且能够评估疗效。就18F-FDG PET/CT在类风湿性关节炎、脊柱关节病、风湿性多肌痛、复发性软骨炎、系统性血管炎、多发性肌炎和皮肌炎、成人斯蒂尔病等活动性RD中的应用进展予以综述。Rheumatic disease(RD)is a group of systemic diseases involving multiple systems,and its pathological change is chronic inflammation of blood vessels and connective tissue.Because 18F-FDG PET/CT can reveal functional and metabolic information,it can be used to semi-quantatively evaluate the severity and systemic involvement extent of the active RD and therapeutic effect at a molecular level.In this article the clinical application of 18F-FDG PET/CT in evaluation of active RD,such as rheumatoid arthritis,spondyloarthropathies,polymyalgia rheumatica,relapsing polychondritis,systemic vasculitis,polymyositis,dermatomyositis and adult onset Still’s disease,were reviewed.

关 键 词：风湿性疾病 18F-氟脱氧葡萄糖 正电子发射体层成像 体层摄影术 X线计算机 炎性疾病 

分 类 号：R593[医药卫生—内科学] R445.6[医药卫生—临床医学]