转移因子对鸡血清生化指标的影响研究  

Effect of transfer factor on the biochemical index of chicken serum

作　　者：林祚贵 徐磊[1,2] 钟佳莲 Lin Zuogui;Xu Lei;Zhong Jialian(Fujian Vocational College of Agriculture,Fuzhou 350119;Nanjing Tianbang Biotechnology Co.Ltd.,Nanjing 211102)

机构地区：[1]福建农业职业技术学院,福州350119 [2]南京天邦生物科技有限公司,南京211102

出　　处：《福建畜牧兽医》2020年第1期13-16,共4页Fujian Journal of Animal Husbandry and Veterinary medicine

基　　金：2019年度福建省科技计划项目（2019N0025）;2019年度江苏省博士后科研资助计划（2019K072）;2019年度福州市科技计划项目（2019-G-34）;2018年福建省中青年教师教育科研项目（职业院校专项，JZ180531）;2018年福建省禽病防治重点实验室开放基金课题（KF201902）;福建农业职业技术学院省部共建福建省动物保健与食品安全应用技术协同创新中心项目（教职成函〔2019〕10号、闽教科〔2017〕49号）;2016年度福建省科技计划项目（2016S0002）;福建省畜禽疫病防控技术重大研发平台项目（2014N2003）;2019年福建农业职业技术学院科技项目（2019JS005）资助

摘　　要：为了明确转移因子(TF)对鸡血清生化指标的影响,选取德化黑鸡,分别以0.5 mL/羽、1.0 m L/羽的剂量肌肉注射TF,连续3 d,作为试验组1和试验组2,并设立仅注射生理盐水的对照组,于最后一次注射后第24 h,采血检测总蛋白、白蛋白、肌酐、Y-谷氨酰基转移酶、总胆红素、尿素、尿酸、丙氨酸氨基转移酶、天门冬氨酸氨基转移酶、甘油三酯、总胆固醇共11个血清生化指标。结果显示,注射TF后试验组1和试验组2总蛋白浓度呈上升趋势,试验组1和试验组2极显著高于对照组(P<0.01),试验组2极显著高于试验组1(P<0.01);试验组白蛋白浓度显著低于对照组(P<0.05),试验组1显著低于试验组2(P<0.05);试验组1尿酸浓度极显著低于对照组(P<0.01),试验组2极显著高于对照组(P<0.01);TF对其他各项生化指标影响均未达到显著水平(P<0.05)。研究结果表明,连续肌肉注射3 d的剂量,TF可极显著提高总蛋白浓度,显著降低白蛋白浓度,0.5 mL/羽连续肌肉注射3 d的剂量极显著降低尿酸浓度,1.0 mL/羽连续肌肉注射3 d的剂量极显著提高尿酸浓度,TF有利于鸡的免疫力提高。In order to clarify the effect of transfer factor(TF)on chicken serum biochemical indicators,Dehua black chicken was selected to inject TF with a dose of 0.5 mL/feather and 1.0 mL/feather,respectively,continuous 3 d as test group 1 and test group 2,And set up a control group that only injected saline,24 h after the last injection,Blood collection to detect total protein,albumin,creatinine,Y-glutamyl transferase,total bilirubin,urea,uric acid,alanine aminotransferase,aspartic acid aminotransferase,triglyceride,total cholesterol A total of 11 serum biochemical indicators.The results showed that the concentrations of total protein in test group 1 and test group 2 showed an increasing trend.Test group 1 and test group 2 were significantly higher than control group(P<0.01),test group 2 was significantly higher than test group 1(P<0.01);The albumin solubility test group was significantly lower than the control group(P<0.05),test group 1 is significantly lower than test group 2(P<0.05);Uric acid concentration test group 1 was significantly lower than control group(P<0.01),the 2 pole of the test group was significantly higher than that of the control group(P<0.01);The influence of TF on other biochemical indicators has not reached a significant level(P>0.05).The results showed that continuous intramuscular injection of 3 d TF could significantly increase the total protein solubility and decrease the albumin solubility,and 0.5 mL/feather continuous intramuscular injection of 3 d TF could significantly decrease the uric acid solubility 1.0 mL/feather continuous intramuscular injection for 3 d significantly increased uric acid solubility,TF was beneficial to the immune enhancement of chickens.

关 键 词：转移因子 德化黑鸡 血清生化指标 

分 类 号：S858.31[农业科学—临床兽医学]