功能性下丘脑性闭经研究进展  

Research Progress on Functional Hypothalamic Amenorrhea

作　　者：马世月 朱梅(审校)[2] MA Shi-yue;ZHU Mei(Beijing Shunyi District Maternal and Child Health Hospital,Beijing 101300,China;Beijing Hospital of Traditional Chinese Medicine Affiliated to the Capital Medical University,Beijing 100010,China)

机构地区：[1]北京市顺义区妇幼保健院,101300 [2]首都医科大学附属北京中医医院

出　　处：《国际生殖健康／计划生育杂志》2020年第1期67-70,共4页Journal of International Reproductive Health/Family Planning

摘　　要：功能性下丘脑性闭经(functional hypothalamic amenorrhea,FHA)是除外下丘脑、垂体等器质性病变,由于循环中促性腺激素和雌激素水平均低而导致的一种好发于年轻女性的中枢性闭经,对女性心血管系统、骨骼系统、生殖系统和心理健康等多方面造成极大的威胁。体内外各种诱发因素,如过度运动、营养缺乏、节食减肥、精神应激或其组合都可导致FHA的发生。FHA的治疗手段包括增加体质量、减少剧烈运动、促性腺激素释放激素脉冲治疗、雌孕激素替代疗法和认知行为疗法。现就功能性下丘脑性闭经的相关研究进展进行综述。Functional hypothalamic amenorrhea(FHA) is characterized by the low levels of serum gonadotropin and estrogen in young women, in which the organic lesion of hypothalamus and hypophysis has been excluded. FHA has negative effects on the cardiovascular system, skeletal system, reproductive system and mental health of patients. Many factors may induce FHA, such as excessive exercise, nutritional deficiencies, dieting, and mental stress, or the combination of those factors. The treatment of FHA should be comprehensive, including the increased weight, the reduced strenuous-exercise, gonadotropin releasing hormone pulse therapy, hormone replacement therapy and cognitive behavioral therapy. The research progress of functional hypothalamic amenorrhea is reviewed.

关 键 词：闭经 下丘脑-垂体系统 运动 体重减轻 神经性厌食 功能性下丘脑性闭经 

分 类 号：R711.51[医药卫生—妇产科学]