抗抑郁药用于慢性疼痛治疗的处方分析  

Prescription Analysis of Anti-Depressants in the Treatment of Chronic Pain

作　　者：孙玥 黄富宏[1] 林郁 刘春吉 SUN Yue;HUANG Fuhong;LIN Yu;LIU Chunji(The Affiliated Hospital of Yangzhou University,Yangzhou,Jiangsu,China 225001;Xuzhou Medical University,Xuzhou,Jiangsu,China 221004)

机构地区：[1]扬州大学附属医院,江苏扬州225001 [2]徐州医科大学,江苏徐州221004

出　　处：《中国药业》2020年第4期60-62,共3页China Pharmaceuticals

基　　金：江苏省扬州市科技计划项目[YZ2018167];江苏省药学会—天晴临床药学基金科研项目[Q2019127]

摘　　要：目的为慢性疼痛的规范化治疗提供参考。方法选取扬州大学附属医院2016年4月1日至2017年4月1日门急诊使用抗抑郁药治疗慢性疼痛的处方进行汇总分析。结果该院门急诊处方中涉及抗抑郁药的处方共5945张,其中用于治疗慢性疼痛的处方共714张(12.01%),涉及14种抗抑郁药,用药多集中在30 d内,2~4种药物联用;涉及12个科室,患者年龄多为46~65岁,女性多于男性;疾病多涉及慢性继发性内脏痛、慢性神经病理性疼痛、慢性继发性头痛和颌面部痛。结论该院门急诊慢性疼痛治疗中抗抑郁药物的使用基本合理。Objective To provide reference for the standardized treatment of chronic pain.Methods Prescriptions for chronic pain in outpatient and emergency treatment in the Affiliated Hospital of Yangzhou University from April 1,2016 to April 1,2017 were selected for analysis.Results A total of 5945 anti-depressant prescriptions were included in the outpatient emergency prescriptions of the hospital,of which 714(12.01%)prescriptions were used to treat chronic pain,involving 14 anti-depressants.The medications were concentrated within 30 d and combination of 2 to 4 drugs;involved 12 departments,and patients were mostly 46-65 years old,with more women than men;diseases mostly involved chronic secondary visceral pain,chronic neuropathic pain,chronic secondary headache and maxillofacial pain.Conclusion The use of antidepressants in the treatment of chronic pain in this hospital is basically rational.

关 键 词：抗抑郁药物 慢性疼痛 处方分析 合理用药 

分 类 号：R969.3[医药卫生—药理学] R971.43[医药卫生—药学]