应用耳针联合地黄饮子治疗血管性痴呆的临床观察  

Clinical observation of the treatment of vascular dementia with auricular acupuncture combined with Dihuangyinzi

作　　者：张相鹏 武密山[2] 袁超 袁龙明越 王红霞 张培红 武宁 曹东义 ZHANG Xiang-peng;WU Mi-shan;YUAN Chao;YUAN Long-ming-yue;WANG Hong-xia;ZHANG Pei-hong;WU Ning;CAO Dong-yi(Graduate School of Hebei University of Traditional Chinese Medicine,Shijiazhuang 050011,China;Hebei Medical University,Shijiazhuang 050031,China;Taishan Center for Disease Control and Prevention,Tai'an 271000,China;Tai'an First Middle School,Tai'an 271000,China;Hebei Provincial Academy of Chinese Medicine,Shijiazhuang 050031,China)

机构地区：[1]河北中医学院研究生院,河北石家庄050011 [2]河北医科大学,河北石家庄050031 [3]山东省泰安市泰山区疾病预防控制中心,山东泰安271000 [4]山东省泰安市第一中学,山东泰安271000 [5]河北省中医药科学院,河北石家庄050031

出　　处：《时珍国医国药》2019年第11期2670-2672,共3页Lishizhen Medicine and Materia Medica Research

基　　金：国家自然科学基金(81073074);河北省教育厅自然科学研究项目(ZD2019129);国家中医药管理局中医药科研专项(2014ZXA03);河北省中医药管理局科研课题(2013061)

摘　　要：目的验证耳穴联合地黄饮子治疗血管性痴呆的临床疗效。方法临床选取72例血管痴呆患者,随机分为治疗组36例、对照组36例,治疗组采用耳针联合中药地黄饮子加减口服,对照组口服西药奥拉西坦胶囊。结果两组血管性痴呆患者治疗前后临床疗效比较,治疗组88.89%,对照组63.89%,治疗组优于对照组;两组患者治疗前后脑电地形图比较,治疗组63.89%,对照组47.22%,治疗组优于对照组;两组患者治疗前后MMSE、ADL量表评分比较治疗8周末,治疗组NIHSS评分与对照组比较,差异有统计学意义(P<0.01)。治疗第6、8、12周末,治疗组NIHSS评分高于对照组(P<0.05)。结论耳针联合地黄饮子能改善VD患者的认知功能和日常生活能力。Objective To verify the clinical efficacy of auricular acupoint combined with Dihuangyinzi in the treatment of vascular dementia.Methods 72 patients with vascular dementia were randomly divided into treatment group(36 cases) and control group(36 cases). The treatment group was treated with auricular acupuncture combined with traditional Chinese medicine Dihuangyinzi. The control group received oral administration of oxiracetam capsules.Results The clinical efficacy of patients with vascular dementia before and after treatment was 88.89% in the treatment group and 63.89% in the control group. The treatment group was superior to the control group. The electroencephalogram topography of the two groups before and after treatment was 63.89% in the treatment group and 47.22% in the control group, the treatment group was superior to the control group;the MMSE and ADL scale scores of the two groups before and after treatment were compared at 8 weeks, and the NIHSS score of the treatment group was significantly different from the control group(P<0.01).At the 6 th, 8 th, and 12 th week of treatment, the NIHSS score of the treatment group was higher than that of the control group(P<0.05). Conclusion Auricular acupuncture combined with Dihuangyinzi can improve the cognitive function and daily living ability of patients with VD.

关 键 词：肾藏精 耳穴 地黄饮子 血管性痴呆 

分 类 号：R259[医药卫生—中西医结合] R285.6[医药卫生—中医内科学]