腹腔镜术式对卵巢妊娠疗效及HCG、E2、FSH的影响  

Effect of laparoscopy on ovarian pregnancy and HCG, E2 and FSH

作　　者：王宁[1] 陈蕾[1] Wang Ning;Chen Lei(Department of Gynaecology and Obstetrics,The Sixth Medical Center of PLA General Hospital,Beijing 100048,China)

机构地区：[1]解放军总医院第六医学中心妇产科

出　　处：《北京医学》2020年第1期32-34,共3页Beijing Medical Journal

摘　　要：目的探讨腹腔镜术式对卵巢妊娠患者的疗效及对人绒毛膜促性腺激素(human chorionic gonadotropin,HCG)、雌二醇(estradiol,E2)、卵泡刺激素(follicular stimulating hormone,FSH)水平的影响。方法选择2008年4月至2018年4月解放军总医院第六医学中心收治的卵巢妊娠患者94例,按照手术方法不同分为观察组和对照组,对照组行传统开腹手术治疗,观察组行腹腔镜手术治疗。比较两组临床疗效,手术前后血清HCG、E2、FSH水平,术后并发症发生情况。结果观察组与对照组相比,观察组手术时间[(53.2±3.2)min比(70.5±4.3)min]、术中出血量[(22.5±1.8)ml比(71.3±3.5)ml]、术后肛门排气时间[(14.9±1.1)h比(20.6±1.7)h]、住院时间[(3.7±0.4)d比(5.8±1.0)d]明显降低,差异均有统计学意义(P<0.05);观察组术后血清HCG[(4.5±2.6)U/L]、E2[(744.8±84.9)pmol/L]明显低于对照组[(8.8±2.1)U/L、(822.4±76.9)pmol/L],而血清FSH水平[(7.7±2.0)U/L]高于对照组[(6.0±1.6)U/L],差异均有统计学意义(P<0.05);观察组术后并发症发生率为8.51%,明显低于对照组(34.04%,P<0.05)。结论腹腔镜术式对卵巢妊娠患者的疗效显著,有利于促进患者早日康复,同时有效改善血清HCG、E2、FSH水平,降低术后并发症发生风险。安全性较好,值得临床推广应用。Objective To study the effect of laparoscopic surgery on ovarian pregnancy and the levels of human chorionic gonadotropin(HCG),estradiol(E2)and follicular stimulating hormone(FSH).Methods Ninety-four cases of ovarian pregnancy admitted to The Sixth Medical Center of PLA General Hospital,from April 2008 to April 2018 were studied.They were divided into the observation group and the control group.The control group was treated with traditional open surgery,while the observation group was treated with laparoscopic surgery.The clinical efficacy of the two groups and serum levels of HCG,E2 and FSH before and after surgery,as well as the occurrence of postoperative complications were compared.Results Compared with the control group,the operation duration[(53.2±3.2)min vs.(70.5±4.3)min],intraoperative blood loss[(22.5±1.8)ml vs.(71.3±3.5)ml],postoperative anal exhaust time[(14.9±1.1)h vs.(20.6±1.7)h]and hospital stay[(3.7±0.4)d vs.(5.8±1.0)d]in the observation group were significantly less(P<0.05).Serum levels of HCG[(4.5±2.6)U/L]and E2[(774.8±84.9)pmol/L]in the observation group were lower than those in the control group[(8.8±2.1)U/L,(822.4±76.9)pmol/L],while serum FSH levels[(7.7±2.0)U/L]was higher in the observation group than that in he control group[(6.0±1.6)U/L,P<0.05].The incidence of postoperative complications in the observation group(8.51%)was lower than that in the control group(34.04%,P<0.05).Conclusions Laparoscopic surgery has a significant effect on the patients with ovarian pregnancy,which is conducive to promoting the early recovery of patients,effectively improving the serum HCG,E2,FSH level,and reducing the risk of postoperative complications.Therefore,it is worthy of clinical application.

关 键 词：卵巢妊娠 腹腔镜手术 人绒毛膜促性腺激素 雌二醇 卵泡刺激素 

分 类 号：R713.6[医药卫生—妇产科学]