肠道菌群与疾病相关性的研究进展  

Advances in research on the relationship between intestinal flora and diseases

作　　者：张静 王肖枭 周怡 王雪 顾开明 叶迎春 ZHANG Jing;WANG Xiao-xiao;ZHOU Yi;WANG Xue;GU Kai-ming;YE Ying-chun(Laboratory of Pathogenic Biology and Medical Immunology,School of Clinical Medicine Sciences,Southwest Medical University,Luzhou 646000,China)

机构地区：[1]西南医科大学基础医学院病原生物学与医学免疫学实验室

出　　处：《基础医学与临床》2020年第2期243-247,共5页Basic and Clinical Medicine

基　　金：2017年国家级大学生创新创业训练项目(201710632045)

摘　　要：肠道菌群数量庞大、种类繁多,其与宿主相互依存、相互影响。人体许多疾病的发生发展以及病情的转归都与肠道菌群有密不可分的联系。肠道微生物通过调节糖、脂质以及氨基酸等物质的代谢影响代谢疾病的发生与发展;肠道菌群紊乱还可促进炎性肠病与某些肠道肿瘤,补充益生菌可有助于这类疾病的治疗;此外,肠道菌群还与神经精神系统、心血管系统、泌尿系统等其他系统的疾病有着千丝万缕的联系。因此研究肠道菌群与疾病的相关性对疾病的预防与治疗,维护人类健康具有重大意义。The quantity of intestinal flora is large and diverse,its interaction with the host.The intestinal flora is closely related to the development and the recovery of many human diseases.Intestinal microorganisms affect the occurrence and development of metabolic diseases by regulating the metabolism of substances such as sugar,lipids and amino acids;intestinal flora disorders can also promote inflammatory bowel disease and certain intestinal tumors,and supplementing probiotics can contribute to treat those diseases;In addition,the intestinal flora is closely related to other system such as the neuropsychiatric system,the cardiovascular system,and the urinary system.Therefore,studying the correlation between intestinal flora and disease is of great significance for the prevention and treatment of those diseases and the maintenance of human health.

关 键 词：肠道菌群 代谢性疾病 炎性肠病 精神类疾病 心血管疾病 

分 类 号：R37[医药卫生—病原生物学]