微生物营养物质代谢与微生物-肠-脑轴互作研究进展  

Progress in Microbial Nutrient Metabolism and Microbiota-Gut-Brain Axis Interaction

作　　者：王后福 李鹏飞 矣国 冷静[2] WANG Houfu;LI Pengfei;YI Guo;LENG Jing(Key Laboratory of Animal and Feed Science of Yunnan Province,Yunnan Agricultural University,Kunming 650201,China;Faculty of Animal Science and Technology,Yunnan Agricultural University,Kunming 650201,China)

机构地区：[1]云南农业大学,云南省动物营养与饲料重点实验室,昆明650201 [2]云南农业大学动物科学技术学院,昆明650201

出　　处：《动物营养学报》2020年第1期28-35,共8页CHINESE JOURNAL OF ANIMAL NUTRITION

基　　金：国家自然科学基金项目(31672452,31060314);云岭产业技术领军人才项目;云南省科技厅重点研发计划——红河黄牛种质资源开发利用(2018BB001-2);云南省现代农业(肉羊)产业技术体系项目(2017KJTX0016-5)

摘　　要：微生物在人和动物胃肠道内含量极为丰富,其在肠道与脑之间的交流通信过程中发挥着重要影响。微生物、肠道和脑之间存在神经、体液和免疫途径双向通信的系统,即微生物-肠-脑轴,其参与调控胃肠道微生物稳态和大脑功能及机体行为。本文通过总结与微生物-肠-脑轴相关的微生物营养物质代谢、能量稳态、作用途径和宿主健康的研究成果,旨在为动物营养物质代谢调控提供一定的参考。Microbiota are abundant in the gastrointestinal tract of humans and animals,which play a key role in the communication between the gastrointestinal tract and the brain.There is a bidirectional communication sys tem of nerves,body fluids and immune pathways among microbiota,gut and brain,that is,microbiota gut brain axis,which regulates the body’s microbial homeostasis,brain function and normal behavior.This review summarized the research results of nutrition metabolism,energy homeostasis,action pathways and host health of the microbiota gut brain axis,aiming to provide some references for the regulation of nutrient metabolism in animals.

关 键 词：微生物-肠-脑轴 微生物代谢 互作途径 能量代谢 健康 

分 类 号：S811[农业科学—畜牧学]