宫颈炎分泌物支原体检测与抗生素敏感性的研究  

Detection of mycoplasma and antibiotic susceptibility in cervicitis secretion

作　　者：罗小娟[1] 杨泽伟 Luo Xiaojuan;Yang Zewei(Department of Clinical Laboratory,The First People's Hospital of Foshan City,Foshan 528000,China)

机构地区：[1]佛山市第一人民医院检验科,528000

出　　处：《国际医药卫生导报》2020年第1期94-96,共3页International Medicine and Health Guidance News

摘　　要：目的分析宫颈炎患者分泌物支原体分布情况及对抗生素的敏感性。方法本次纳入对象为本院妇科、皮肤科2018年6月至2019年6月收治的宫颈炎患者200例,采集宫颈分泌物进行支原体培养和药敏试验,并分析其对9种抗生素的敏感性。结果200例宫颈炎患者支原体检出率为48.5%,其中Mh占1.5%,Uu占33.5%,Uu+Mh占13.5%;Uu对抗生素的敏感性排序为美满霉素(97.0%)、交沙霉素(95.5%)、克拉霉素(95.5%)及强力霉素(91.0%),耐药性为司帕沙星(34.3%)和氧氟沙星(29.9%);Uu+Mh对抗生素的敏感性为美满霉素(85.2%)、交沙霉素(81.5%)、强力霉素(70.4%),耐药性为罗红霉素(88.9%)、阿奇霉素(81.5%)、克拉霉素(74.1%)及司帕沙星(74.1%)。结论Uu、Uu+Mh为宫颈炎患者支原体感染的主要类型,临床需结合药敏试验针对性选择抗生素,确保治疗效果最优。Objective To analyze the distribution of mycoplasma of secretion in patients with cervicitis and the sensitivity to antibiotics.Methods 200 cases of cervicitis patients were included in the department of gynecology and dermatology of our hospital from June 2018 to June 2019.The cervical secretions were collected for mycoplasma culture and drug susceptibility test,and their sensitivity to 9 antibiotics were analyzed.Results The detection rate of mycoplasma in 200 patients with cervicitis was 48.5%,of which Mh accounted for 1.5%,Uu accounted for 33.5%,Uu+Mh accounted for 13.5%.The sensitivity of Uu to antibiotics ranked as minocycline(97.0%),josamycine(95.5%),clarithromycin(95.5%),and doxycycline(91.0%),the resistance to antibiotics ranked as sparfloxacin(34.3%)and ofloxacin(29.9%);the sensitivity of Uu+Mh to antibiotics ranked as minocycline(85.2%),josamycin(81.5%),doxycycline(70.4%),the resistance to antibiotics ranked as roxithromycin(88.9%),azithromycin(81.5%),clarithromycin(74.1%),and sparfloxacin(74.1%).Conclusion The Uu and Uu+Mh are the main types of mycoplasma infection in patients with cervicitis.Clinically,antibiotics should be selected in combination with drug sensitivity test to ensure the best therapeutic effect.

关 键 词：宫颈炎 分泌物 支原体检测 抗生素 敏感性 

分 类 号：R4[医药卫生—临床医学] R711