硼中子俘获疗法在医疗船上的应用与可行性设计研究  

Application and Feasibility Design Research of Boron Neutron Capture Therapy on Medical Ship

作　　者：郭志家[1] 范月容[1] 昝怀啟[1] 万海霞[1] 柯国土[1] 陈会强[1] GUO Zhijia;FAN Yuerong;ZAN Huaiqi;WAN Haixia;KE Guotu;CHEN Huiqiang(Division of Reactor Engineering Technology Research)

机构地区：[1]中国原子能科学研究院反应堆工程技术研究部

出　　处：《原子能科学技术》2020年第2期320-326,共7页Atomic Energy Science and Technology

摘　　要：硼中子俘获疗法(BNCT)是一种能选择性地阻击癌细胞的生物靶向放射治疗方法,该治疗方法在医疗船上的应用设想是基于IAEA癌症关怀项目,旨为非洲等发展中国家提供癌症医疗援助及其他医疗服务。本文介绍了医疗船的中子照射治疗模块,该模块以国内已建成的医院中子照射器-1型(IHNI-1)为设计原型,根据船用反应堆的特殊环境和工况要求,对反应堆水池的外形、屏蔽材料的选型、堆本体系统和设备的结构以及中子照射治疗模块的总体布置进行设计优化。分析表明该设计理念和方案具备一定的开发价值和应用可行性。Boron neutron capture therapy(BNCT) is a biologically-targeted radiotheraphy method that can selectively block cancer cells. The application of this treatment method in medical ship is based on IAEA cancer care project, aiming to provide cancer medical assistance and other medical services for developing countries in Africa or other continents. Neutron irradiation theraphy module of the ship was introduced in this paper, and the module was based on the design prototype of in-hospital neutron irradiator-1(IHNI-1) built in China. According to the requirements of special environment and condition of marine reactor, the shape of reactor pool, the selection of shielding material, the structure of reactor complex system and equipment and the general layout of neutron irradiation theraphy module were optimized. The analysis shows that the design concept and scheme have some development value and application feasibility.

关 键 词：硼中子俘获疗法 医疗船 医院中子照射器 中子照射治疗模块 设计优化 

分 类 号：TL99[核科学技术—核技术及应用]