静脉预注小剂量甲氧明预防老年患者全身麻醉诱导期低血压的效果观察  

Effect of Intravenous Pre-injection of Low Dose Methoxamine on the Prevention of Hypotension During Induction of General Anesthesia in Elderly Patients

作　　者：孙雪峰[1] 庞博[1] 曲茹[1] SUN Xuefeng;PANG Bo;QU Ru(Jiamusi City Central Hospital,Jiamusi 154002,China)

机构地区：[1]黑龙江省佳木斯市中心医院

出　　处：《中国医学创新》2019年第36期37-40,共4页Medical Innovation of China

基　　金：黑龙江省卫生厅项目（2010-406）

摘　　要：目的:观察静脉预注小剂量甲氧明预防老年患者全身麻醉诱导期低血压的效果。方法:随机选取2016年1月-2018年1月于本院需全身麻醉手术的老年患者200例作为研究对象,采用随机数字表法分为研究组和对照组,每组100例。诱导麻醉前研究组预注静脉注射甲氧明,对照组静脉注射0.9%氯化钠溶液。比较两组的麻醉效果、清醒时间、平均动脉压、手术成功率、麻醉诱导期低血压发生率及并发症发生情况。结果:研究组麻醉效果优良率高于对照组(P<0.05);研究组清醒时间明显短于对照组(P<0.05);研究组平均动脉压优于对照组(P<0.05);研究组手术成功率高于对照组(P<0.05);研究组麻醉诱导期低血压发生率及并发症发生率均低于对照组(P<0.05)。结论:在老年患者诱导麻醉前预注小剂量甲氧明可以有效加快患者清醒时间,保证手术麻醉效果,有效减少麻醉诱导期低血压及并发症的发生,值得临床推广。Objective:To observe the effect of intravenous pre-injection of low dose Methoxamine on preventing hypotension during induction of general anesthesia in elderly patients.Method:A total of 200 elderly patients needed general anesthesia surgery in our hospital from January 2016 to January 2018 were randomly selected as the study objects.They were divided into study group and control group by random number table method,100 cases in each group.Before induction anesthesia,the study group was given intravenous injection of Methoxamine,while the control group was given intravenous injection of 0.9% Sodium Chloride Solution.The anesthesia effect,waking time,mean arterial pressure,success rate of operation,incidence of hypotension in anesthesia induction period and incidence of complications were compared between the two groups.Result:The rate of excellent anesthesia effect in the study group were higher than those in the control group(P<0.05).The awake time in the study group was significantly lower than that in the control group(P<0.05).The mean arterial pressure in the study group was better than that in the control group(P<0.05).The success rate of operation in the study group was higher than that in the control group(P<0.05).The incidence of hypotension during anesthesia induction period and complications in the study group were lower than those in the control group(P<0.05).Conclusion:Pre-injection of low dose Methoxamine before induction of anesthesia in elderly patients can effectively accelerate patients’waking time and ensure the effect of surgical anesthesia,effectively reduce the occurrence of hypotension during induction of anesthesia and complications,which is worthy of clinical promotion.

关 键 词：静脉预注 甲氧明 全身麻醉 低血压 

分 类 号：R614[医药卫生—麻醉学]