纵向峰值应变离散度及收缩期峰值应变评价系统性红斑狼疮患者左心室收缩功能  

Longitudinal Peak Strain Dispersion and Systolic Peak Strain in Evaluating Left Ventricular Systolic Function of Patients with Systemic Lupus Erythematosus

作　　者：李帅 袁建军 朱好辉 吴铭 吕诗佳 李思靓 LI Shuai;YUAN Jianjun;ZHU Haohui;WU Ming;LV Shijia;LI Siliang(Department of Ultrasound,Zhengzhou University People´s Hospital,Zhengzhou 450003,China)

机构地区：[1]郑州大学人民医院超声科

出　　处：《中国医学影像学杂志》2020年第2期95-98,共4页Chinese Journal of Medical Imaging

摘　　要：目的探讨纵向峰值应变离散度、收缩期峰值应变评价系统性红斑狼疮(SLE)患者左心室心肌收缩同步性及收缩功能的价值。资料与方法选取确诊为SLE的60例患者,根据病程分为Ⅰ组(病程≤5年)和Ⅱ组(病程>5年),每组30例;选取健康志愿者30例为对照组,比较3组受试者的一般资料、超声心动图常规参数、纵向峰值应变离散度(PSD)、纵向收缩期峰值应变(GLS)、圆周收缩期峰值应变(GCS)及径向收缩期峰值应变(GRS)的差异。结果3组受试者一般资料及超声心动图常规参数两两比较,差异均无统计学意义(P>0.05)。3组间两两比较,Ⅰ、Ⅱ组患者的PSD均高于对照组,且Ⅱ组的PSD高于Ⅰ组(P均<0.05)。Ⅰ、Ⅱ组患者的GLS均低于对照组(P<0.05),但Ⅰ、Ⅱ组患者GLS比较,差异无统计学意义(P>0.05)。Ⅱ组GCS及GRS较Ⅰ组和对照组均下降,差异均有统计学意义(P<0.05),Ⅰ组GCS及GRS与对照组接近,差异均无统计学意义(P>0.05)。结论PSD及GLS能早期评价SLE患者左心室收缩的同步性及收缩功能的变化。Purpose To investigate the value of longitudinal peak strain dispersion and systolic peak strain in evaluating left ventricular myocardial synchronization and contractile function in patients with systemic lupus erythematosus(SLE).Materials and Methods Sixty patients with confirmed SLE were selected and divided into groupⅠ(course of disease≤5 years)and groupⅡ(course of disease>5 years),30 cases in each group;30 healthy volunteers were selected as the control group.General information of three groups of subjects,general parameters of echocardiography,longitudinal peak strain dispersion(PSD),longitudinal systolic peak strain(GLS),circumferential systolic peak strain(GCS),and radial systolic peak strain(GRS)among three groups were compared.Results There was no significant difference in the general information and conventional echocardiographic parameters among the three groups of subjects(P>0.05).PSD of the patients in groupⅠandⅡwas higher than that in control group,and PSD of groupⅡwas higher than that in groupⅠ(P<0.05).The GLS of patients in groupⅠandⅡwere lower than those in control group(P<0.05),but there was no significant difference in GLS between patients in groupⅠandⅡ(P>0.05).The GCS and GRS in groupⅡwere significantly lower than those in groupⅠand control group(P<0.05).The GCS and GRS in groupⅠwere significantly close to the control group(P>0.05).Conclusion PSD and GLS can early evaluate the left ventricular systolic synchronization and changes of systolic function in patients with SLE.

关 键 词：红斑狼疮 系统性 超声心动描记术 多普勒 彩色 斑点追踪成像 心室功能 左 心肌收缩 

分 类 号：R593.2[医药卫生—内科学] R445.1[医药卫生—临床医学]