中药及其有效成分对细胞焦亡的影响研究进展  

Research Progress on the Effects of Traditional Chinese Medicine and the Active Ingredients on Cell Pyroptosis

作　　者：胡晋婷 马萍[1] HU Jin-ting;MA Ping(Chengdu University of Traditional Chinese Medicine,Chengdu,610075,China)

机构地区：[1]成都中医药大学,四川成都610075

出　　处：《时珍国医国药》2019年第12期2968-2970,共3页Lishizhen Medicine and Materia Medica Research

基　　金：国家自然科学基金(81173365);四川省中医药管理局科学技术研究专项基金(2018JC008)。

摘　　要：细胞焦亡是一种新型细胞死亡方式,在感染性疾病、红斑狼疮、骨髓异常增生综合征、动脉粥样硬化、阿兹海默症以及代谢性疾病等的发生发展中广泛参与,是针对外源性感染和机体内源性危险信号产生的防御反应,能促使被感染细胞程序性死亡和机体炎症的发生.该文将对中药及其有效成分对细胞焦亡的影响进行综述,为后续研究提供参考.Cell pyroptosis as a new type of cell death is widely involved in the occunence and development of infectious diseases,lupus erythematosus,myelodysplastic syndrome,atherosclerosis,Alzheimer and metabolic diseases.In addition to,pyroptosis is a defensive response to exogenous infection and endogenous danger signals,which induces programmed cell death in infected cells and inflammation.In this paper,the effects of traditional Chinese medicine and its active ingredients on cell pyroptosis are reviewed,for providing reference for follow-up research.

关 键 词：细胞焦亡 中药 提取物 

分 类 号：R285.5[医药卫生—中药学]