关节置换术后假体周围感染的实验室诊断  

Laboratory diagnosis of periprosthetic joint infection after total joint arthroplasty

作　　者：潘允琪 汤瑾[1] 王坚镪[1] 李运改 PAN Yunqi;TANG Jin;WANG Jianqiang;LI Yungai(Department of Clinical Laboratory,Shanghai Sixth People's Hospital,Shanghai 200233,China)

机构地区：[1]上海市第六人民医院检验科

出　　处：《检验医学》2020年第1期75-78,共4页Laboratory Medicine

摘　　要：关节假体周围感染(PJI)是关节置换术后发生的严重并发症,需尽快明确诊断、积极治疗,以避免产生严重的不良后果。由于实验室传统检查方法敏感性和特异性的限制,PJI的诊断至今仍面临巨大挑战。近年来,一些兼具高敏感性和高特异性的检测方法,包括生物标志物检测和病原学检测方法在PJI诊断方面具有良好的应用前景。文章对关节置换术后PJI早期诊断的研究进展作一综述,以便为临床诊治提供参考。Periprosthetic joint infection(PJI)is a serious complication in total joint arthroplasty patients,which leads to severe consequences if unresolved timely.Because of the low sensitivity and specificity of the conventional diagnostic tools,the diagnosis of PJI is still a challenge in modern medicine.In the recent years,some new diagnostic techniques,with high sensitivity and specificity,such as biomarker determination and the culture of pathogenic bacteria,have been developed.This review is to provide a comprehensive and up-to-date review on the diagnostic strategies for PJI.

关 键 词：假体周围感染 实验诊断 生物标志物 微生物学技术 

分 类 号：R446.1[医药卫生—诊断学]