代谢组学技术在奶牛生产性疾病研究中的应用  

Application of Metabolomics Technology in Studies of Productive Diseases in Dairy Cows

作　　者：韦人月 郑家三[1] WEI Ren-yue;ZHENG Jia-san(Heilongjiang Bayi Agricultural University,Daqing 163319,China)

机构地区：[1]黑龙江八一农垦大学

出　　处：《畜牧与饲料科学》2020年第1期18-22,共5页Animal Husbandry and Feed Science

基　　金：黑龙江八一农垦大学研究生科研创新资助项目（YJSCX2018-Y23）;国家科技支撑计划项目“规模化奶牛场群发病综合防控关键技术集成与示范”（2012BAD12B05-2）;国家科技支撑计划项目“奶牛养殖业节能减排关键技术研究与示范”（2013BAD21B01）

摘　　要：代谢产物是基因转录翻译为蛋白质后生命活动的最终执行者,因此,机体代谢产物的变化可以直接反映出生物体内各种生命活动的变化。运用代谢组学技术可以清晰并直观地对机体代谢物的变化进行检测。奶牛生产性疾病一直是畜牧兽医行业关注的重点疾病之一。奶牛出现生产性疾病会直接或间接导致奶牛生产性能下降,对养殖业造成危害。代谢组学技术的应用可以更加全面地了解疾病的发生发展过程,准确检测出参与疾病发生的物质和代谢通路,使兽医更加有针对性地开展疾病防控和治疗。综述了代谢组学技术在奶牛生产性疾病研究中的应用,以期为今后奶牛生产性疾病的防控和治疗提供思路。Metabolites are the ultimate executor of life activities after gene transcription and translation into proteins.Therefore,changes in metabolites can directly reflect the variations in various life activities in the body.Using metabolomics technology can clearly and intuitively detect the changes in the body′s metabolites.Productive diseases in dairy cows have been the clinically significant diseases in animal husbandry and veterinary medicine industry.The occurrence of productive diseases in dairy cows will directly or indirectly lead to a decline in the production performance of dairy cows and bring economic losses to the breeding industry.The application of metabolomics technology can help to more comprehensively understand the occurrence and development of diseases,accurately detect the substances and metabolic pathways involved in disease occurrence,and enable veterinarians to carry out targeted prevention,control and treatment of diseases.In this paper,the application of metabolomics technology in the researches of dairy cow′s productive diseases is reviewed,in hoping to provide insight into the prevention and control of these diseases in dairy farms in the future.

关 键 词：代谢组学 奶牛 营养代谢病 繁殖障碍疾病 肢蹄病 

分 类 号：S858.23[农业科学—临床兽医学]