儿童紫癜性肾炎的诊治进展  

Diagnosis and treatment of children with purpura nephritis

作　　者：张廷廷(综述) 姜红(审校)[1] Zhang Tingting;Jiang Hong(Department of Pediatrics,the First Affiliated Hospital of China Medical University,Shenyang 110001,China;Department of Pediatrics,Shandong Third Hospital,Jinan 250031,China)

机构地区：[1]中国医科大学附属第一医院儿科,沈阳110001 [2]山东省立第三医院儿科,济南250031

出　　处：《国际儿科学杂志》2019年第12期859-863,共5页International Journal of Pediatrics

摘　　要：紫癜性肾炎是儿童时期最常见的继发性肾脏疾病,为免疫复合物介导的肾小球损伤,大部分患儿临床表现轻微,仅表现为镜下血尿或微量蛋白尿,只有少部分患儿表现为肾功能不全。国内外对紫癜性肾炎的诊断明确,不管是临床分型还是病理分级都有共识,但目前国际上还没有统一的治疗方案,大多认为早诊断、早治疗对预后影响深远,尤其对于持续蛋白尿者更应积极采取多种药物联合治疗以降低进展为慢性肾功能不全的概率。Henoch-Schonlein purpura nephritis is the most common secondary renal disease in children,which is caused by immune complex mediated glomerular injury.Most children show mild symptoms,only presenting as microscopic hematuria or microalbuminuria,and a few children show renal insufficiency.The diagnosis of purpura nephritis is clear at home and abroad.Both clinical classification and pathological grading have consensus,but there is no unified treatment on the international at present.Early diagnosis and treatment have a profound effect on prognosis.Especially for the continuous proteinuria,multi-drug treatment should be taken to reduce the probability of progression to chronic renal insufficiency.

关 键 词：儿童 紫瘢性肾炎 诊断 治疗 

分 类 号：R72[医药卫生—儿科]