具有抗肿瘤活性环金属铂自组装超分子研究进展  

Research progress on self-assembly cyclometalated Platinum supramolecules with antitumor activity

作　　者：黄翔 吕涛 肖亚宝 丁宝月[1] 寿炎祺 敖雷[1] Huang Xiang;Lu Tao;Xiao Yabao;Ding Baoyue;Shou Yanqi;Ao Lei(Jiaxing College,Zhejiang Jiaxing 314001;Zhejiang Tailison Pharmaceutical Co.,Ltd-,Zhejiang Jiaxing 314300)

机构地区：[1]嘉兴学院 [2]浙江泰利森药业有限公司

出　　处：《云南化工》2020年第1期10-12,共3页Yunnan Chemical Technology

基　　金：嘉兴学院大学生科研训练计划（SRT）项目（NO.851719227）;浙江省公益性技术应用研究计划项目（NO.LGF20H160031,LGF18H160034）;国家自然科学基金面上基金(NO.81872220)

摘　　要：恶性肿瘤是严重威胁人类健康的疾病,受到全世界广大学者的极大关注。不同的金属自组装超分子在药物递送体系中研究广泛,并且也有不同侧面的综述报道,而自组装超分子直接用于抗肿瘤的研究报道比较少见。综述了具有抗肿瘤活性含环金属铂的自组装超分子的研究进展。Malignant tumors are a serious threat to human health, which have received great attention from researchers around the world. Resently, different metals self-assembly supramolecules have been widely studied in drug delivery systems, and there have also been reports of different aspects on this topic.However, reports on the use of self-assembly supramolecules for antitumor are rare. This article is focus on research progress of self-assembly supramolecules with cyclometalated platinum directly in antitumor activity.

关 键 词：自组装 超分子 环金属铂 抗肿瘤 

分 类 号：TB383.1[一般工业技术—材料科学与工程]