中心动脉血压变异性与高血压左心房扩大的关系  

Central blood pressure variability is increased in hypertensive patients with enlarged left atrium

作　　者：曾学寨[1] 刘德平[1] 王丽娟[2] 徐筑津 张晏[4] 王华[1] 张瑞生[1] 周济红 潘春宇[1] 甘宇 乔巍巍[1] Zeng Xuezhai;Liu Deping;Wang Lijuan;Xu Zhujin;Zhang Yan;Wang Hua;Zhang Ruisheng;Zhou Jihong;Pan Chunyu;Gan Yu;Qiao Weiwei(Department of Cardiology,Beijing Hospital,National Center of Gerontology,Institute of Geriatrics Medicine,Chinese Academy of Medical Sciences,Beijing 100730,China)

机构地区：[1]北京医院心内科国家老年医学中心中国医学科学院老年医学研究院,北京100730 [2]北京医院营养科国家老年医学中心中国医学科学院老年医学研究院,北京100730 [3]北京医院放射科国家老年医学中心中国医学科学院老年医学研究院,北京100730 [4]北京医院特需病房国家老年医学中心中国医学科学院老年医学研究院,北京100730

出　　处：《中国临床保健杂志》2020年第1期45-50,共6页Chinese Journal of Clinical Healthcare

基　　金：国家自然科学基金(51672030)

摘　　要：目的探讨中心动脉血压变异性与高血压左心房扩大的关系。方法入选原发性高血压136患者,行24 h动态血压监测(采用Mobil-O-Graph NG动态血压监测仪测量中心动脉及肱动脉血压变异性)和超声心动图检查。结果高血压左心房扩大患者46例(33.8%),与左心房正常的高血压患者相比,左心房扩大高血压患者脉压增大;24 h肱动脉收缩压标准差、24 h中心动脉收缩压标准差增大。经血压校正后回归分析显示24 h中心动脉收缩压标准差与高血压左心房扩大相关,而24 h肱动脉收缩压标准差未达显著性。结论左心房扩大的高血压患者肱动脉、中心动脉收缩压变异性增高,中心动脉收缩压变异性可能与左心房扩大相关。Objective To explore the relationship between central blood pressure variability and left atrial enlargement in patients with hypertension.Methods The blood pressure variability of central artery and brachial artery was measured by Mobil-O-Graph NG ambulatory blood pressure monitor.136 patients with essential hypertension,aged(55±14)years,72%men were studied.Results 46 patients had left atrial enlargement(33.8%).Compared with the patients with normal left atrium,the pulse pressure of patients with left atrium enlargement increased significantly;the 24 h standard deviation of brachial systolic pressure and central systolic pressure increased significantly.Regression analysis after blood pressure correction showed that the standard deviation of 24 h central systolic pressure was significantly correlated with left atrial enlargement in hypertension,while the standard deviation of 24 h brachial systolic pressure was not significant.Conclusion Systolic blood pressure variability of brachial artery and central artery is increased in hypertensive patients with left atrial enlargement,and systolic blood pressure variability of central artery may be correlated with left atrial hypertrophy.

关 键 词：原发性高血压 左心房 动脉压 超声心动描记术 

分 类 号：R54[医药卫生—心血管疾病]