食品接触材料中羟酸迁移量的研究  

Migration of Hydroxylic Acids in Food Contact Materials

作　　者：杨璐 周国桁 申丽霞 张智力 许超 YANG Lu;ZHOU Guoheng;SHEN Lixia;ZHANG Zhili;XU Chao(Shandong Provincial Key Laboratory of Test Technology for Material Chemical Safety,Shandong Institute Product Quality Inspection,Jinan 250102,China)

机构地区：[1]山东省产品质量检验研究院山东省材料化学安全检测技术重点实验室

出　　处：《中国塑料》2020年第2期79-84,共6页China Plastics

基　　金：2018年山东省产品质量检验研究院科研储备项目(2018ZJKY001)

摘　　要：采用高效液相色谱内标法同时检测食品接触材料中对苯二甲酸、间苯二甲酸、顺丁烯二酸3种羟酸的迁移量。从流动相、流动相梯度、紫外波长3个方面对色谱条件进行了优化,并计算了方法的检出限、定量限、回收率和相对标准偏差,最后,按照优化后的色谱条件测试了样品中对苯二甲酸、间苯二甲酸、顺丁烯二酸的迁移量。结果表明,在1~20 mg/L范围内线性良好,相关系数R>0. 999,回收率为98. 3%~109. 7%,相对标准偏差为0. 14%~3. 75%,方法准确度、精密度高;11 min内完成一次检测,分析效率高,是一种简单、经济的方法;在正常使用条件下,样品中对苯二甲酸、间苯二甲酸、顺丁烯二酸的迁移量符合限量要求,证实了食品接触材料的安全性,而误用条件下的安全评价需进一步试验。The migration of three types of hydroxylic acids(terephthalic acid,isophthalic acid and maleic acid)in plastic food contact materials was determined simultaneously by a HPLC internal standard method.The chromatographic conditions were optimized in terms of the mobile phase,mobile phase gradient and ultraviolet wavelength,and the detection limit,quantitative limit,recovery rate and relative standard deviation were calculated.Furthermore,the migration amounts of terephthalic acid,phthalic acid and maleic acid from the samples were measured under the optimized chromatographic conditions.The results indicated that the test data exhibited a good linear relationship in the concentration range of 1~20 mg/L with a correlation coefficient of R>0.999,a recovery rate of 98.3%~109.7%and a relative standard deviation of 0.14%~3.75%.This method has a high accuracy and precision and also shows high analysis efficiency by presenting a test time within 11 min.Under the general test conditions,the migration amounts of terephthalic acid,isophthalic acid,and maleic acid in the samples were found to meet the requirements of the safety limitation of food contact materials.However,the safety evaluation should be further conducted under the misuse conditions.

关 键 词：高效液相色谱 对苯二甲酸 间苯二甲酸 顺丁烯二酸 迁移试验 

分 类 号：TQ317[化学工程—高聚物工业]