依折麦布联合辛伐他汀对老年心绞痛合并高LDL-C患者的短期疗效观察  

Therapeutic effect of Ezetimibe combined with Simvastatin applied to Senile angina pectoris patients companied by high LDL-C

作　　者：盛红宇[1] 周冬梅 库沙尼·热依汉 狄明莉 SHENG Hongyu;ZHOU Dongmei;Kushani·Reihan;DI Mingli(General medicine department of the people s hospital of Changji Hui autonomous prefecture,Xinjiang 831100,China)

机构地区：[1]新疆昌吉回族自治州人民医院全科医学科

出　　处：《中国老年保健医学》2020年第1期64-66,共3页Chinese Journal of Geriatric Care

摘　　要：目的探讨依折麦布联合辛伐他汀治疗老年心绞痛合并高低密度脂蛋白胆固醇(LDL-C)患者的疗效。方法随机选取2018年3月至12月老年心绞痛合并高LDL-C患者102例,将其分为观察组和对照组,每组51例,对照组采用辛伐他汀20mg口服治疗,观察组采用依折麦布10mg联合辛伐他汀20mg口服治疗,比较两组患者的LDL-C水平和心绞痛恢复情况。结果对照组的总有效率为74.5%,观察组的总有效率为96.1%,治疗组的效果明显优于对照组(P<0.05)。结论在治疗老年心绞痛合并高LDL-C患者时,采用依折麦布联合辛伐他汀有着良好的临床效果,可以有效降低LDL-C水平,缓解患者心绞痛的发生,提高治疗效果,值得临床重视和应用。Objective To discuss therapeutic effect of ezetimibe combined with simvastatin applied to elderly angina pectoris patients companied by high LDL-C.Methods Randomly selected 102 senile angina pectoris patients combined with higher LDL-C from March to December 2018,Randomly divided patients into observation group and control group,25 cases in each group,control group with simvastatin therapy,observation group ezetimibe combined with simvastatin,compared the patient’s level of LDL-C and angina pectoris between two groups.Results The control group total effective rate was 74.5%,the observation group total effective rate was 96.1%,the effect of the treatment group was obviously better than that of control group(P<0.05).Conclusion To elderly angina pectoris patients companied by high LDL-C,ezetimibe combined with simvastatin acquired good result,can effectively reduce the level of LDL-C,alleviate the occurrence of angina pectoris patients,improve the treatment effect,to pay highly attention and application in clinic.

关 键 词：依折麦布 辛伐他汀 老年心绞痛 低密度脂蛋白胆固醇(LDL-C) 

分 类 号：R589.2[医药卫生—内分泌] R541.4[医药卫生—内科学]