和、补、固、攻四法论治解脲脲原体感染性不育症  

The Treatment of Ureaplasma urealyticum Infertility in 4 Methods of Harmony,Supplement, Solid, and Attack

作　　者：周海亮 周兴[2] 李波男 何清湖[1] ZHOU Hailiang;ZHOU Xing;LI Bonan;HE Qinghu(School of Integration of Chinese and Western Medicine,Hunan University of Chinese Medicine,Changsha,Hunan 410208,China;The First Affiliated Hospital of Hunan University of Chinese Medicine,Changsha,Hunan 410007,China)

机构地区：[1]湖南中医药大学中西医结合学院,湖南长沙410208 [2]湖南中医药大学第一附属医院,湖南长沙410007

出　　处：《湖南中医药大学学报》2020年第2期160-164,共5页Journal of Hunan University of Chinese Medicine

基　　金：国家自然科学基金资助项目（81673984、81774324）;湖南省自然科学基金资助（2018JJ3402）;湖南省教育厅优秀青年项目（16B200）;长沙市杰出创新青年人才项目（kq1802015）;湖南省高层次卫生人才225工程医学学科骨干人才培养对象（湘卫函〔2019〕196号）;湖南创新型省份建设专项经费资助-“湖湘青年英才”支持计划（2019RS2041）

摘　　要：男性生殖系解脲脲原体感染是男性不育症的重要致病原因,其病理为感染破坏生殖系免疫稳态,产生多种炎症因子,从而诱导生精细胞凋亡、影响精液质量。根据其流行病学、病理特征及临床表现,运用循证医学审因求证,中医学认为其基本病机为肾虚、湿热血瘀证,病性为虚实夹杂。本文运用景岳经典《新方八阵》之和、补、固、攻四法,结合临床实践,共同探讨解脲脲原体感染性男性不育症证治。Ureaplasma urealyticum infection in male reproductive system is an important cause of male infertility,and the pathology is that Ureaplasma urealyticum infection disrupts germline immune homeostasis,producing a variety of inflammatory factors,inducing spermatogenic cell apoptosis and affecting sperm quality.According toepidemiology,pathological features and clinical manifestations,evidence-based medicine review for verification was applied.Chinese medicine believes that the basic pathogenesis is kidney Yin deficiency,and dampness-heat blood stasis syndrome.The nature of the disease is intermingled deficiency and excess.Based on the 4 methods of harmony,supplement,solid and attack from Jing yue’s classic,Xinfang Bazhen,this paper jointly discusses the treatment of male infertility caused by ureaplasma urealyticum infection by combining clinical practice.

关 键 词：解脲脲原体 感染性不育症 张景岳 新方八阵 和法 补法 固法 攻法 

分 类 号：R256.56[医药卫生—中医内科学] R698.2[医药卫生—中医学]