[BMim]Im催化的高效合成苯偶姻的绿色合成  

Green Synthesis Strategy of Benzoin Catalyzed by [BMim]Im

作　　者：成乐琴[1] 张跃伟[1] 王兆东 CHENG Le-qin;ZHANG Yue-wei;WANG Zhao-dong(School of Chemistry and Pharmaceutical Engineering,Jilin Institute Chemical Technology,Jinlin Jilin 132022,China)

机构地区：[1]吉林化工学院化学与制药工程学院

出　　处：《广州化工》2020年第2期37-40,72,共5页GuangZhou Chemical Industry

基　　金：校级重大科研项目(2016004);校级科研项目(2017011)

摘　　要：以氮杂环卡宾离子液体[BMim]Im作为催化剂,利用单因素实验和正交实验探索并优化了由苯甲醛合成苯偶姻的工艺条件。产物通过红外分析和核磁共振分析进行了结构确认。实验最优条件为:苯甲醛(新蒸)5 mL,50%NaOH水溶液1.1 mL,THF 20 mL作为溶剂,55℃下搅拌3 min,最高产率可达89.4%。该方法的显著优点是易于后处理,产率高,重现性好,反应时间短。The process conditions for the synthesis of benzoin from benzaldehyde were investigated and optimized by single factor experiment and orthogonal experiment with N-heterocyclic carbine ionic liquids[BMim]Im.The structure of product was confirmed by infrared analysis and nuclear magnetic resonance analysis.The optimized conditions were as follows:using benzaldehyde(new steamed)5 mL,50%NaOH(aq)1.1 mL and THF 20 mL as the solvents,stirred at 55℃for 3 min,the highest yield could reach 89.4%.The remarkable advantages of this method were easy work-up,higher yield,good reproducibility and shorter reaction time.

关 键 词：苯偶姻 安息香缩合 咪唑类离子液体 绿色合成 

分 类 号：O625.4[理学—有机化学]