高强度聚焦超声联合GnRH-a治疗子宫腺肌症临床疗效分析  被引量:2

Clinical Efficacy Analysis of HIFU Combined with GnRH-a in the Treatment of Adenomyosis

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作  者:李洁明[1] 张艳[1] 谢珊莉 LI Jie-ming;ZHANG Yan;XIE Shan-li(Department of Obstetrics and Gynecology,The First People’s Hospital of Guangyuan,Guangyuan Sichuan 628000,China)

机构地区:[1]广元市第一人民医院妇产科

出  处:《医学食疗与健康》2019年第18期1-2,共2页Medical Diet and Health

摘  要:目的:探讨HIFU联合GnRH-a治疗子宫腺肌症临床疗效。方法:选取已确诊子宫腺肌症患者134例,其中70例为实验组行HIFU联合GnRH-a治疗。64例为对照组行单纯HIFU治疗,比较两组术后子宫体积及病灶体积缩小率变化、症状改善情况、总复发率、痛经评分及月经量评分。结果:实验组术后3个月痛经及月经增多缓解总有效率、术后6个月实验组痛经缓解总有效率及术后12个月实验组痛月经增多缓解总效率高于对照组(P<0.05);实验组子宫体积缩小和病灶体积缩小率均明显高于对照组,总复发率显著低于对照组(P<0.05);实验组痛经评分、月经量评分水平均明显低于对照组(P<0.05)。结论:HIFU联合GnRH-a治疗较单纯性行HIFU治疗可明显降低复发率,延迟复发,适合年龄较大,病程较长的子宫腺肌症患者。Objective:To investigate the clinical efficacy of HIFU combined with GnRH-a in the treatment of adenomyosis.Methods:134 patients with adenomyosis were chosen and divided into 2 groups including control group(64 patients)with GnRH-a and experiment group(70 patients)with HIFU combined with GnRH-a;and the uterine volume,lesion volume reduction rate,symptom improvement,total recurrence rate,dysmenorrhea score and menstrual volume score after operation of 2 groups were compared.Results:The total effective rate of relieving dysmenorrhea and menstrual increase in 3 months after operation,total effective rate of relieving dysmenorrhea in 6 months after operation and total effective rate of menstrual increase in 12 months after operation of experimental group were significantly higher than control group(P<0.05).The uterine volume reduction rate and lesion volume reduction rate in the experimental group were significantly higher than control group,and the total recurrence rate were significantly lower than that control group(P<0.05).The dysmenorrhea score and menstrual volume score in the experimental group were significantly lower than control group(P<0.05).Conclusion:HIFU combined with GnRH-a in the treatment of adenomyosis can significantly reduce the recurrence rate and delay recurrence compared with simple HIFU treatment.It is suitable for older patients with adenomyosis with longer course of disease.

关 键 词:子宫腺肌症 高强度聚焦超声 促性腺激素释放激素 

分 类 号:R445.1[医药卫生—影像医学与核医学] R711.71[医药卫生—诊断学]

 

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