血清降钙素原在滇藏线重症交通创伤患者感染中的作用与应用  

The Role and Application of Serum Procalcitonin in Infections of Patients Suffering Severe Traffic Trauma on Yunnan-Tibet Highway

作　　者：李倩[1] 杨政标 朱麒宇 张胜梅[1] Li Qian;Yang Zhengbiao;Zhu Qiyu;Zhang Shengmei(Department of Clinical Laboratory,32268 Army of Chinese PLA,Dali,Yunnan 671003,China)

机构地区：[1]中国人民解放军32268部队检验科

出　　处：《大理大学学报》2020年第2期76-79,共4页Journal of Dali University

摘　　要：目的:探讨血清降钙素原(PCT)在滇藏线重症交通创伤患者感染中的临床作用。方法:选取2015年1月至2017年12月在滇藏线沿线发生交通事故后被收治到中国人民解放军32268部队(原解放军第60中心医院)的以颅脑外伤、肝脾破裂、胸腹联合伤或多发伤为主的重症患者1396例,对其进行PCT及血培养、分泌物培养连续检测的观察,分析PCT在诊断滇藏线重症交通创伤患者感染中的价值。结果:感染组患者PCT水平显著高于对照组[(5.38±2.71)vs.(0.56±0.42)ng/mL,P<0.01];PCT在诊断滇藏线重症交通创伤患者感染中ROC曲线下面积为[0.897(0.778~0.981),P<0.01];感染组患者发热24 h时血培养的阳性率为16.39%,而PCT检测阳性率为80.60%;革兰阴性菌感染的患者PCT水平明显高于革兰阳性菌感染的患者。结论:PCT可以作为滇藏线重症交通创伤患者感染的诊断指标。Objective:To investigate the clinical effects of serum procalcitonin in patients who suffered severe traffic trauma on YunnanTibet Highway.Methods:From January 2015 to December 2017,1396 patients with severe head injuries,liver and spleen ruptures,thoracoabdominal injuries or multiple injuries who were admitted to 32268 Army of Chinese PLA after traffic accidents on Yunnan-Tibet Highway were selected and observed for PCT,blood culture and secretion culture.The value of PCT in diagnosing the infections of patients who suffered severe traffic trauma on Yunnan-Tibet Highway was analyzed.Results:The PCT level of patients in the infected group was significantly higher than that in the control group[(5.38±2.71)vs.(0.56±0.42)ng/mL,P<0.01];the area under ROC curve of PCT in the diagnosis of patients who suffered severe traffic trauma on Yunnan-Tibet Highway was[0.897(0.778-0.981),P<0.01];The positiverateofbloodculturewas 16.39%andPCTwas 80.60%intheinfectedgroupafter 24 hoursoffever.PCTlevelofpatientsinfected with gram-negative bacilli was significantly higher than that of patients infected with gram-positive bacilli.Conclusion:PCT can be usedasadiagnosticindexforinfectionsofpatientswhosufferedseveretraffictraumaonYunnan-TibetHighway.

关 键 词：降钙素原 滇藏线 重症 交通伤 感染 

分 类 号：R446.1[医药卫生—诊断学]