2004-2019年某院乳腺早发育及乳腺发育症临床资料分析  

Analysis of clinical characteristics of premature thelarche and the gynecomastia from 2004 to 2019

作　　者：张菊嫦 王学青[2] 罗洁 梁柱心 祝志敏[1] 陈锐[1] 邱少东[1] ZHANG Juchang;WANG Xueqing;LUO Jie;LIANG Zhuxin;ZHU Zhimin;CHEN Rui;QIU Shaodong(Department of Ultrasound,the Second Affiliated Hospital of Guangzhou Medical University,Guangzhou,Guangdong 510260,China;Huiqiao Medical Center of Nanfang Hospital,Southern Medical University,Guangzhou,Guangdong 510515,China)

机构地区：[1]广州医科大学附属第二医院超声科,广州510260 [2]南方医科大学附属南方医院惠侨中心,广州510515

出　　处：《重庆医学》2020年第4期582-585,共4页Chongqing medicine

摘　　要：目的分析2004年5月1日至2019年4月30日某院乳腺早发育及乳腺发育症患者的临床资料随时间变化情况。方法回顾性收集2004年5月1日至2019年4月30日该院行彩超检查诊断为乳腺早发育及乳腺发育症的病例,根据年龄,将纳入的768例患者分为8岁以下和8岁及其以上两组,再根据时间,分为2004年5月1日至2009年4月30日(T1)、2009年5月1日至2014年4月30日(T2)和2014年5月1日至2019年4月30日(T3)3组,分别比较检出率、年龄、年龄分布等资料。结果一共纳入768例患者,其中8岁以下组,共113例,8岁及以上组,共655例。T1、T2、T3组乳腺发育总的检出率分别是0.68%(37/5430)、1.32%(264/20043)和1.43%(467/32673),总检出率呈先上升后平稳趋势(χ^2=19.57,P=0.000),T2组检出率比T1组明显上升(χ^2=13.96,P=0.000),T2、T3组比较差异无统计学意义。在8岁以下组、8岁及以上组乳腺发育例数是增加的,分别从T1组的1例和36例增加到T3组的85例和382例。年龄分布曲线发现两个年龄组里3个时间段乳腺发育的年龄分布具有相似趋势,而且在4~8岁及10~20岁存在乳腺发育人数增长速度增快的现象。结论2004年5月1日至2019年4月30日该院乳腺发育的检出率呈先升高后趋向平稳趋势,其检出的平均年龄、年龄分布等随时间变迁有相似的趋势,但是在4~8岁及10~20岁年龄阶段增长速度较快。Objective To analyze the clinical characteristics of premature thelarche and the gynecomastia from May 1,2004 to April 30,2019.Methods The clinical data of 768 patients diagnosed with premature thelarche or gynecomastia were collected retrospectively.Patients were divided into two groups at the line of age 8.Then,according to the time of diagnosis,patients in both groups will be further divided into three groups labeled May 1,2004 to April 30,2009(T1),May 1,2009 to April 30,2014(T2)and May 1,2004 to April 30,2019(T3)respectively.Then detective rates,age and age distribution were analyzed.Results 768 cases were included,with 113 cases in the group of children smaller than 8 years old,while 655 cases in the group of males older than 8 years old.The detective rates of premature thelarche and the gynecomastia in group T1,T2,T3 were 0.68%(37/5430),1.32%(264/20043)and 1.43%(467/32673)respectively,which had risen between the first two period(χ^2=13.96,P=0.000),while the rise between the last two period was of no significant difference.The number of the patients diagnosed with premature thelarche or gynecomastia increased in both age groups,which increased from 1 and 36 cases at T1 to 85 and 382 cases at T3 respectively.The age distribution curves showed that the age distribution had the similar trends in both age groups,but at the age range of 4-8 years old and 10-20 years old,the speed of patients diagnosed with premature thelarche or gynecomastia increased.Conclusion The detective rate of premature thelarche and gynecomastia had increased at first and then come to a relative steady level.The clinical characteristics kept relatively stable with time going-by,but the increase speed did increase at the age range of 4-8 years old and 10-20 years old.

关 键 词：乳腺 人 临床特征 变化 

分 类 号：R445.1[医药卫生—影像医学与核医学]