12例破伤风临床救治分析  

Analysis of clinical characteristics of 12 cases of patients with tetanus

作　　者：童学成[1] 王慧雯 徐天敏[1] Tong Xuecheng;Wang Huiwen;Xu Tianmin(Department of Infectious Diseases,The Third People’s Hospital of Changzhou,Jiangsu Changzhou 213001,China)

机构地区：[1]常州市第三人民医院感染科

出　　处：《新发传染病电子杂志》2020年第1期32-34,共3页Electronic Journal of Emerging Infectious Diseases

摘　　要：目的分析破伤风的临床资料,总结重症破伤风的救治经验,降低破伤风的病死率。方法回顾性分析2010年1月至2019年5月常州市第三人民医院感染科、普外科、重症医学科收治的12例破伤风患者的临床资料。结果12例破伤风患者中,男8例,女4例,年龄(57.4±14.8)岁,潜伏期3~60d,中位数11d。职业构成以农民和工人为主(10例)。有明确外伤史者8例,临床表现为发热、张口受限、腰背疼痛、肢体抽搐、呼吸困难;重症病例9例,患者入院后经伤口处理、中和毒素、抗感染、控制痉挛、呼吸支持及营养支持等综合治疗,10例治愈,2例死亡。结论成人破伤风易出现重症,早诊断,尽早综合治疗,可减轻病情,降低病死率。Objective To analyze the clinical data of 12 cases of tetanus,summarize the experience of treatment of severe tetanus in order to reduce the mortality of tetanus.Methods A retrospective study was conducted to analyze the clinical data of 12 tetanus patients admitted by the department of infectious diseases,general surgery and intensive care unit of the Third People’s Hospital of Changzhou from January 2010 to May 2019.Results Among the twelve patients,8 were male and 4 were female,and the mean age was(57.4±14.8)years.The average incubation period is 3~60 days.The occupational composition is dominated by farmers and workers(8 cases).There were 8 cases(66.7%)with a clear history of trauma.Clinically,the most frequent symptoms observed were fever,trismus,low back pain,limb spasms,and difficulty in breathing.After admission,9 cases of severe cases were treated with wound treatment,toxin neutralization,anti-infection,spasticity control,respiratory support and nutritional support,among which 10 cases were cured and 2 cases died.Conclusions Tetanus of adult is prone to severe disease,so early diagnosis,comprehensive treatment can reduce disease and mortality.

关 键 词：破伤风 临床特征 治疗 

分 类 号：R517.3[医药卫生—内科学]