米索前列醇促宫颈成熟1天后低宫颈评分的处理方法比较  

The comparison of 3 induction managements on term pregnant women with low bishop scores after one-day misoprostol induction

作　　者：曹冬如 陈磊[1] 马瑶[1] 白月婷[1] 赵怿 杨明芳[1] CAO Dongru;CHEN Lei;MA Yao;BAI Yueting;ZHAO Yi;YANG Mingfang(Department of Obstetrics,Haidian Maternal and Child Health Hospital,Beijing 100080,China)

机构地区：[1]北京市海淀区妇幼保健院产科

出　　处：《中国性科学》2020年第2期75-78,共4页Chinese Journal of Human Sexuality

摘　　要：目的对应用米索前列醇促宫颈成熟治疗1天后,宫颈Bishop评分仍低于6分的孕妇,比较3种不同处理方法的有效性和安全性。方法选取2016年1月至2019年5月海淀区妇幼保健院诊治的162例孕妇作为研究对象。均具有引产指征且已应用米索前列醇阴道上药促宫颈成熟1天。将其随机分为甲、乙、丙三组,甲组继续应用米索前列醇阴道上药1天,共59人,乙组改用宫颈水囊促宫颈成熟1天,共60人,丙组直接缩宫素静点1天,共43人。结果①三组宫颈评分比较,差异具有统计学意义(P<0.05)。三组干预前后宫颈条件比较,甲组及乙组干预后宫颈评分明显高于入组前宫颈评分,差异具有统计学意义(P<0.05),丙组干预后宫颈评分与干预前宫颈评分比较差异无统计学意义(P>0.05)。②三组阴道分娩率比较,差异具有统计学意义(P<0.05)。三组引产失败率比较,差异具有统计学意义(P<0.05)。阴道分娩出血量、产后出血≥500mL的产妇数、宫腔感染/产褥感染的产妇数、新生儿感染数、1min Apgar评分及新生儿体重三组比较,差异无统计学意义(P>0.05)。结论对于应用米索前列醇促宫颈成熟1天后宫颈评分低的孕妇,继续应用宫颈水囊有效且安全。Objective To evaluate the efficacy and safety of 3 induction managements on term pregnant women who had undergone one-day misoprostol induction and with the cervical bishop score lower than 6.Methods 162 pregnant women were chosen,and all of them had induction indication and had undergone one-day misoprostol induction.The 162 women were divided into 3 groups randomly,59 women were in group A and subsequently used misoprostol induction for a day.60 women were in group B and used water balloon induction for a day.43 women were in group C and used drip of oxytocin for a day.Results①There were statistically significant differences in the cervical bishop scores among the 3 groups(P<0.05).There were statistically significant differences in the cervical bishop scores in group A and group B between before and after intervention(P<0.05),while no statistically significant difference was found in group C(P>0.05).②There were statistically significant differences in the rates of vaginal delivery and rate of induction failure among the 3 groups(all P<0.05).There was no statistically significant difference in the amount of bleeding during vaginal delivery,number of women with postpartum hemorrhage≥500 mL,number of women with intrauterine infection or puerperal infection,neonatal infection,1 min Apgar scores and neonatal weight(P>0.05).Conclusions The cervical water balloon is effective and safe for pregnant women having undergone one-day misoprostol induction and with the cervical bishop scores lower than 6.

关 键 词：米索前列醇 宫颈水囊 促宫颈成熟 

分 类 号：R714[医药卫生—妇产科学]