双侧突发性聋27例临床分析  

A clinical analysis of 27 cases of simultaneous bilateral sudden sensorineural hearing loss

作　　者：孙常领[1] 过丹尼 沈佳[1] 杜晓东[1] SUN Changling;GUO Danni;SHEN Jia;DU Xiaodong(Department of Otolaryngology Head and Neck Surgery,Affiliated Hospital of Jiangnan University,Wuxi,214062,China)

机构地区：[1]江南大学附属医院耳鼻咽喉头颈外科

出　　处：《临床耳鼻咽喉头颈外科杂志》2019年第12期1134-1137,共4页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

基　　金：无锡市青年医学人才项目(No:QNRC054)

摘　　要：目的:比较双侧同时发病的突发性聋(Si-BSSHL)与单侧突发性聋(USSHL)的临床特点和治疗效果。方法:回顾性分析27例Si-BSSHL患者的临床资料,包括发病特点、临床表现、听力学检查、血液学检查及治疗效果等,并与同期发病的139例USSHL患者进行比较。结果:Si-BSSHL组的发病年龄\[(65.85±9.17)岁\]明显高于USSHL组\[(56.95±13.18)岁\],差异有统计学意义(P<0.01);2组男女比例差异无统计学意义(P>0.05);Si-BSSHL伴眩晕、耳胀满感和既往患有高血压、糖尿病、冠心病、中风的比例与USSHL相比差异无统计学意义(P>0.05),伴耳鸣的比例明显低于USSHL组(P<0.05);Si-BSSHL组听力损失程度分布和听力曲线类型与USSHL组相比差异有统计学意义,Si-BSSHL组治疗前PTA和极重度听力损失的比例明显低于USSHL组(P<0.05),下降型听力曲线明显多于USSHL组(P<0.01);Si-BSSHL组的纤维蛋白原明显高于USSHL组(P<0.05),血小板平均体积、甘油三酯、叶酸等指标与USSHL组比较差异无统计学意义(P>0.05);Si-BSSHL组治疗总有效率为44.44%,USSHL组为41.73%,2组差异无统计学意义(P>0.05)。结论:Si-BSSHL更多见于高龄患者,女性比例较高,与USSHL相比,Si-BSSHL听力损失程度较轻,极重度聋患者所占比例较少,下降型听力曲线更多,治疗效果无明显差异。Objective:To compare the clinical characteristics and therapeutic effects between simultaneous bilateral sudden sensorineural hearing loss(Si-BSSHL)and unilateral sudden sensorineural hearing loss(USSHL).Method:The clinical data of 27 cases of Si-BSSHL were retrospectively analyzed,including the characteristics of the disease,clinical manifestations,audiological examination,hematological examination,and therapeutic effect,and compared with those of 139 cases of USSHL.Result:There was a statistically significant difference in the age(65.85±9.17 vs 56.95±13.18,P<0.01)and no significant difference in sex ratio(P>0.05)between the two groups.The proportion of Si-BSSHL patients with vertigo,ear fullness,hypertension,diabetes,coronary heart disease and stroke had no statistical difference compared with those of USSHL(P>0.05),the proportion of patients with tinnitus in Si-BSSHL group was significantly lower than that in USSHL group(P<0.05).The distribution of hearing loss degree and the type of audiometry in Si-BSSHL group were significantly different from those in USSHL group,PTA before treatment and the proportion of profound hearing loss in Si-BSSHL group was significantly lower than that in USSHL group(P<0.05),descending audiometry type was more common in Si-BSSHL group compared to USSHL(P<0.01).Fibrinogen in Si-BSSHL group was significantly higher than that in USSHL group(P<0.05).No significant difference was found between the two groups with respect to mean platelet volume,blood lipid and folic acid(P>0.05).The total treatment effective rate in Si-BSSHL group was 44.44%,while that in USSHL group was 41.73%,there was no significant difference between the two groups(P>0.05).Conclusion:Si-BSSHL has a female preponderance and tends to occur in advanced age in our cohort.Compared to USSHL patients,Si-BSSHL patients have less profound hearing loss and more descending audiograms,and the proportion of patients with extremely severe deafness is relatively small.There is no significant difference in the therapeutic effect

关 键 词：聋 突发性 听力学 治疗效果 

分 类 号：R764.43[医药卫生—耳鼻咽喉科]