四川省内江市2010-2017年手足口病流行特征及病原学分析  

Epidemiologic Characteristics and Etiology of Hand-Foot-Mouth Disease in Sichuan Neijiang from 2010 to 2017

作　　者：邓德明[1] 皮丹丹[2] 刘刚[3] Deng Deming;Pi Dandan;Liu Gang(The Second People’s Hospital of Neijiang,Sichuan Neijiang 641000,China;Children’s Hospital of Chongqing Medical University,Chongqing 400014,China;The Disease Control and Prevention Center of Neijiang,Sichuan Neijiang 641000,China)

机构地区：[1]四川省内江市第二人民医院,四川内江641000 [2]重庆医科大学附属儿童医院,重庆400014 [3]四川省内江市疾病预防控制中心,四川内江641000

出　　处：《儿科药学杂志》2020年第2期22-25,共4页Journal of Pediatric Pharmacy

摘　　要：目的:分析2010-2017年手足口病在内江市的流行情况及病原学特点,探讨疾病防控工作中存在的问题,为手足口病的防控提供参考。方法:利用描述性统计学分析方法,应用Excel 2003软件对2010-2017年内江市手足口病流行资料进行数据整理和分析。结果:2010-2017年内江市手足口病共报告病例15113例,年发病率为19.53/100000~67.66/100000,平均为50.05/100000。2012年为发病高峰,年发病率达67.66/100000。0~5岁组占总发病人数的94.81%,为手足口病的主要发病人群。散居儿童和幼托儿童在职业分布中占发病总数的98.13%。发病时间全年散发,主要集中在4-7月及10-12月。2010-2017年共采集手足口病患者的血液样本4012例,病毒核酸检测阳性2390例(59.57%),其中,EV71占28.83%(689/2390),CA16占27.24%(651/2390),其他肠道病毒占43.93%(1050/2390)。结论:手足口病在内江市发病率处于相对较高水平,病例全年散发,患者主要为0~5岁人群。为控制手足口病的传播与流行,需加强监测与宣传,扩大疫苗免疫人群,增加疫苗保护的病原谱等措施。Objective:To analyze the epidemiologic characteristics and etiology of hand-foot-mouth disease in Sichuan Neijiang from 2010 to 2017,and to discuss the problems existing in the prevention and control of the disease,so as to provide reference for the prevention and control of hand-foot-mouth disease.Methods:Descriptive epidemio-logical method was adopted,analysis of epidemic data of hand-foot-mouth disease in Neijiang from 2010 to 2017 were conducted by using Excel 2003 software.Results:From 2010 to 2017,a total of 15,113 cases of hand-foot-mouth disease were reported in Neijiang,with an annual incidence of 19.53/100,000 to 67.66/100,000,with an average of 50.05/100,000.The peak incidence of infection was in 2012,with an annual incidence of 67.66/100,000.The main morbidity population was aged from 0 to 5 years old,accounting for 94.81%of the total number.Children in diaspora and childcare accounted for 98.13%of the total number in the occupational distribution.The time of onset mainly distributed from Apr.to Jul.and Oct.to Dec.throughout the year.From 2010 to 2017,a total of 4,012 cases of blood samples were collected from children with hand-foot-mouth disease,and 2,390 cases(59.57%)were positive for viral nucleic acid tests,of which EV71 accounted for 28.83%(689/2,390),CA16 accounted for 27.24%(651/2,390),and other enteric viruses accounted for 43.93%(1,050/2,390).Conclusion:The incidence of hand-foot-mouth disease is at a relatively high level in Neijiang,it is distributed throughout the year and mainly concentrated in children aged from 0 to 5 years.In order to control the spread and prevalence of hand-foot-mouth disease,it is necessary to strengthen the monitoring and publicity,expand the population immunized by vaccine,and increase the pathogen spectrum protected by vaccine.

关 键 词：手足口病 流行特征 传染病 

分 类 号：R725.1[医药卫生—儿科]