去细胞基质水凝胶的治疗研究进展  

Development of Decellularized Matrix Hydrogel Therapies

作　　者：黎婷 张海燕[1] LI Ting;ZHANG Haiyan(College of Biotechnology,Wuhu Institute of Technology,Wuhu,Anhui 241003)

机构地区：[1]芜湖职业技术学院生物工程学院

出　　处：《绵阳师范学院学报》2020年第2期73-77,共5页Journal of Mianyang Teachers＇ College

基　　金：2019年高校优秀拔尖人才培育项目-高校优秀青年骨干人才国内外访学研修项目(GXGWFX2019072);安徽省自然科学研究重点项目(KJ2018A0691);芜湖职业技术学院校级人才项目(WZYRC201801);2019年高校学科拔尖人才学术资助一般项目(GXYQ2019);2018年安徽省教学研究一般项目(2018JYXM0181)

摘　　要：近年来,去细胞基质以多种形态被广泛应用于组织工程,其中水凝胶的应用最为常见.在临床使用上,去细胞基质水凝胶多用注射的方式进行使用,以期免疫排斥反应最小化.去细胞基质水凝胶可从多种组织获得,并以用于多种疾病模型的治疗,如缺血性损伤和器官再生或移植等.本篇综述了去细胞基质水凝胶的体外应用进展,为今后的多种疾病的临床治疗提供更多的思路.In recent years,decellularized matrix hydrogel has been widely used in tissue engineering in different forms,of which hydrogel application is the most common.Decellularized matrix hydrogel often uses injection to minimize the immune rejection response in clinical.Decellularized matrix hydrogels could be derived from a variety of tissues and used in the treatment of several disease models,such as ischemic damage and organ regeneration or transplantation.This review concentrates on the in vitro application progress of decellularized matrix hydrogel and provides more ideas for the clinical treatment in the future.

关 键 词：去细胞 水凝胶 体外 

分 类 号：R318.08[医药卫生—生物医学工程]