纳布啡超前镇痛在老年患者腹腔镜胆囊切除术中的应用研究  

The Application Research of Nalbuphine Preemptive Analgesia in Laparoscopic Cholecystectomy in Elderly Patients

作　　者：廖飞[1] 朱雁鸿[1] 陈静宜[1] Liao fei;Zhu Yanhong;Chen jingyi(People's Hospital Of Yuxi City Of Yunnan Province,Yuxi Of Yunnan Provinee,653100,China)

机构地区：[1]昆明医科大学第六附属医院暨玉溪市人民医院

出　　处：《首都食品与医药》2020年第2期75-76,共2页Capital Food Medicine

摘　　要：目的观察纳布啡超前镇痛在老年患者腹腔镜胆囊切除术中的应用效果。方法选取60例拟在全麻下行腹腔镜胆囊切除术的老年患者,随机分为纳布啡组(N组)和对照组(D组),两组均常规全麻,其中N组于麻醉诱导前15min静脉注射纳布啡0.15mg/kg,D组给予等量生理盐水。观察对比两组手术情况、苏醒及拔管时间、循环变化、镇痛效果等。结果两组苏醒及拔管时间比较无差异(P>0.05);HR、MAP变化:T4时N组无明显波动(P>0.05),而D组与T0时及N组比较明显升高(P<0.05);VAS评分:N组术后各时间点均比D组明显降低(P<0.05或P<0.01)。结论纳布啡超前镇痛对老年患者腹腔镜胆囊切除术有较好镇痛效果,并且循环稳定、不影响苏醒及拔管,值得临床推广。Objective To observe the effect of nalbuphine preemptive analgesia on laparoscopic cholecystectomy in elderly patients.Methods 60 cases of laparoscopic cholecystectomy in elderly patients under general anesthesia were randomly divided into 2 groups,30 cases in each group.Intravenous infusion 15 min before anesthesia induction:Group N received nalbuphine 0.15 mg/kg;group D received equal amount of physiological saline.Observe the operation condition,time of resuscitation and extubation,circulation change,analgesia effect.Results There was no difference between the two groups of awakening and extubation time(P>0.05);HR,MAP:There was no obvious fluctuation in group N at T4(P>0.05),but group D was significantly higher than the T0 and Group N(P<0.05);VAS score:All time points in group N were significantly lower than that in group D(P<0.05 or P<0.01).Conclusion Preemptive analgesia with nalbuphine has a good analgesic effect on elderly patients undergoing laparoscopic cholecystectomy,with stable circulation and does not affect waking and trachea extubation.It is worthy of clinical promotion.

关 键 词：纳布啡 超前镇痛 老年 腹腔镜胆囊切除术 

分 类 号：R614[医药卫生—麻醉学]