中性粒细胞明胶酶相关脂质运载蛋白在急性肾损伤中的最新进展  

Recent advances in neutrophil gelatinase-associated lipocalin in acute kidney injury

作　　者：唐姣琪 邓跃林[1] Tang Jiao-qi;Deng Yue-lin(Department of Emergency Medicine,Xiangya Hospital,Central South University,Changsha 410008,China)

机构地区：[1]中南大学湘雅医院急诊科,湖南长沙410008

出　　处：《中国急救医学》2019年第12期1192-1196,共5页Chinese Journal of Critical Care Medicine

基　　金：中南大学临床大数据系统建设-急性中毒临床大数据系统建设项目(07)。

摘　　要：中性粒细胞明胶酶相关脂质运载蛋白(NGAL)因在急性肾损伤(AKI)中通过多种途径参与肾脏损伤修复,且较传统标志物变化迅速,使其不仅成为AKI早期诊断最具前景的生物学指标之一,同时在病因鉴别和预后判断方面具有重要临床意义.本文主要对NGAL在各种病因诱发的AKI临床应用中的最新研究进展进行综述.Neutrophil gelatinase-associated lipocalin(NGAL)participates in the renal damage and restoration through multiple ways and changes more rapidly compared to traditional markers in acute kidney injury(AKI),which make its become one of the most promising indicators in AKI early diagnosis,at the same time,it has important clinical significance in the differentiation of etiology and prognosis.In this paper,we reviewed the latest research progress of NGAL in the clinical application of AKI induced by various causes.

关 键 词：中性粒细胞明胶酶相关脂质运载蛋白(NGAL) 急性肾损伤(AKI) 研究进展 

分 类 号：R692[医药卫生—泌尿科学]