基于俞募配穴理论针刺天枢、大肠俞治疗功能性腹泻的临床疗效观察  

Effect of Tianshu( ST 25) and Dachangshu( BL 25) on functional diarrhea based on the theory of Shu-Mu point combination

作　　者：赵盼盼 刘智斌 王斌 曹星 金兰 王楠 ZHAO Pan-pan;LIU Zhi-bin;WANG Bin;CAO Xing;JIN Lan;WANG Nan(School of Acupuncture and Moxibustion,Shaanxi University of Chinese Medicine,Xianyang Shaanxi 712046;Acupuncture and Medicine Innovation Institute,Shaanxi University of Chinese Medicine,Xianyang Shaanxi 712046;The Affiliated Hospital of Shaanxi University of Chinese Medicine,Xianyang 712083;Department of Ophthalmology,Xi′an Traditional Chinese Medicine Hospital,Xi′an 710021)

机构地区：[1]陕西中医药大学针灸推拿学院,陕西咸阳712046 [2]陕西中医药大学针药结合创新研究中心,陕西咸阳712046 [3]陕西中医药大学附属医院,陕西咸阳712083 [4]西安市中医医院眼科,陕西西安710021

出　　处：《世界中西医结合杂志》2020年第2期348-351,356,共5页World Journal of Integrated Traditional and Western Medicine

基　　金：国家重点基础研究发展计划(973项目)(2011CB505200)

摘　　要：目的基于俞募配穴理论取天枢、大肠俞治疗功能性腹泻,观察其临床疗效,探讨其作用机理。方法将所招募的患者随机分为针刺组和药物组,针刺组选取双侧天枢、大肠俞,得气后辅以电针治疗;药物组则给予盐酸洛哌丁胺胶囊口服;两组的观测指标均为1周自主排便总次数及粪便性状评分(1周平均分),分别以治疗1周、4周、6周、8周后为观测节点。结果治疗1周后,两组均能使功能性腹泻患者自主排便次数减少(P<0.05),但两组之间比较,差异无统计学意义(P>0.05);治疗4周、6周、8周后,针刺组对患者排便次数的改善仍明显(P<0.01),而药物组对患者排便次数的改善存在反复,两组比较差异有统计学意义(P<0.05,P<0.01)。治疗1周后,两组功能性腹泻患者的粪便性状评分均降低(P<0.05),两组比较疗效未见明显差异(P>0.05);治疗4周、6周、8周后,针刺组对患者粪便性状的改善仍明显(P<0.01),而药物组对患者粪便性状的改善存在反复,两组比较差异有统计学意义(P<0.05,P<0.01)。结论口服盐酸洛哌丁胺胶囊及针刺天枢、大肠俞(配合电针)对治疗功能性腹泻疗效均确切,且近期疗效相当;但与药物组比较,针刺组的疗效更持久、个体差异性较小、安全系数更高。Objective To investigate the effect and mechanism of Tianshu(ST 25)and Dachangshu(BL 25)in treating functional diarrhea,according to the theory of Shu-Mu point combination.Methods Patients were randomly divided into the acupuncture group and medicine group.The acupuncture group was treated by needling on double sides of Tianshu(ST 25)and Dachangshu(BL 25)and after obtaining qi,electroacupuncture was applied.The medicine group was given loperamide hydrochloride capsule for oral use.1-week spontaneous bowel movements and fecal trait score(average score in one week)were observed after 1 w,4 w,6 w,8 w treatment.Results After 1-week treatment,spontaneous bowel movements in both groups significantly decreased(P<0.05),but without significant difference between the two groups(P>0.05).After 4 w,6 w and 8 w treatment,spontaneous bowel movements in the acupuncture group was significantly improved(P<0.01),however,in the medicine group,the symptoms got repeated,with significant difference between the two groups(P<0.05,P<0.01).After 1-week treatment,the fecal trait score in both groups decreased(P<0.05)without significant differences between the two groups(P>0.05).After 4 w,6 w and 8 w treatment,the fecal trait score in the acupuncture group improved significantly(P<0.01),however,the improvement in the medicine group was unstable,with significant difference between the two groups(P<0.05,P<0.01).Conclusion Treatment of loperamide hydrochloride capsules and needling on Tianshu(ST 25)and Dachangshu(BL 25)(with electroacupuncture)are effective in treating functional diarrhea and the short-term efficacy is equivalent.However,compared with the medicine group,the effect of acupunc-turegroup is more persistent and safer with smaller individual differences.

关 键 词：功能性腹泻 天枢 大肠俞 针刺 俞募配穴 

分 类 号：R442.2[医药卫生—诊断学]