磁共振T2-mapping成像定量检测肥胖人群椎间盘早期退变的应用研究  

Application of magnetic resonance T2-mapping imaging in quantitative detection of early intervertebral disc degeneration in obese people

作　　者：贝晶晶 肖华平 邱敏华[1] 陈洁[2] Bei Jingjing;Xiao Huaping;Qiu Minhua;Chen Jie(Department of Radiology,Taizhou Hospital of Traditional Chinese Medicine,Taizhou,Zhejiang 318000,China;Department of Radiology,Taizhou Municipal Hospital,Taizhou,Zhejiang 318000,China)

机构地区：[1]台州市中医院放射科,浙江省318000 [2]台州市立医院放射科,浙江省318000

出　　处：《中国基层医药》2020年第2期138-141,共4页Chinese Journal of Primary Medicine and Pharmacy

基　　金：浙江省台州市科技计划项目(1801ky58)。

摘　　要：目的探讨磁共振T2-mapping成像在肥胖人群椎间盘早期退变诊断中的价值。方法抽取台州市中医院、台州市立医院2018年1月至2019年6月MRI常规检查正常的志愿者60例为观察对象,根据体质量指数分为单纯肥胖组30例和体质量正常的对照组30例,分别进行腰椎间盘磁共振T2-mapping成像,测量并比较两组不同节段椎间盘髓核T2值的差异。结果对照组腰1~2、腰2~3、腰3~4、腰4~5、腰5至骶1节段椎间盘髓核T2值分别为(108.17±10.87)ms、(113.93±11.54)ms、(126.65±10.22)ms、(118.62±8.86)ms、(111.61±10.65)ms,不同节段椎间盘髓核T2值差异有统计学意义(F=14.28,P<0.001);单纯肥胖组腰1~2、腰2~3、腰3~4、腰4~5、腰5至骶1节段椎间盘髓核T2值分别为(104.90±7.67)ms、(101.10±6.61)ms、(112.65±5.75)ms、(98.27±6.18)ms、(89.82±6.34)ms,不同节段椎间盘髓核的T2值差异有统计学意义(F=49.52,P<0.001)。两组腰2~3、腰3~4、腰4~5、腰5至骶1节段椎间盘髓核T2值差异均有统计学意义(t=5.283、6.535、10.327、9.626,均P<0.001)。结论磁共振T2-mapping成像可发现椎间盘退变早期组织成分改变,可以为肥胖人群椎间盘退变的早期诊断提供重要的参考依据。Objective To explore the clinical value of magnetic resonance T2-mapping imaging in the diagnosis of early intervertebral disc degeneration in obese people.Methods From January 2018 to June 2019,30 obese volunteers and 30 healthy volunteers with normal weight underwent T2-mapping scan,while their routine MRI examination showed no abnormalities were slected.The T2 value of nucleus pulposus in both two groups were measured and compared.Results The T2 values of nucleus pulposus of intervertebral disc of lumbar 1-2,lumbar 2-3,lumbar 3-4,lumbar 4-5 and lumbar 5-sacral 1 in the control group were(108.17±10.87)ms,(113.93±11.54)ms,(126.65±10.22)ms,(118.62±8.86)ms and(111.61±10.65)ms,respectively,which of nucleus pulposus in different segments was statistically significant(F=14.28,P<0.001).The T2 values of nucleus pulposus of intervertebral disc of lumbar 1-2,lumbar 2-3,lumbar 3-4,lumbar 4-5,lumbar 5-sacral 1 in the simple obesity group were(104.90±7.67)ms,(101.10±6.61)ms,(112.65±5.75)ms,(98.27±6.18)ms,(89.82±6.34)ms,respectively,,which of nucleus pulposus in different segments was statistically significant(F=49.52,P<0.001).There were statistically significant differences in the T2 values of nucleus pulposus of intervertebral disc of lumbar 2-3,lumbar 3-4,lumbar 4-5,lumbar 5-sacral 1 between the two groups(t=5.283,6.535,10.327,9.626,all P<0.001).Conclusion Magnetic resonance T2-mapping can detect early changes in tissue composition of intervertebral disc degeneration.Therefore,magnetic resonance T2-mapping imaging technology can provide an important reference for the early diagnosis of intervertebral disc degeneration in obese people.

关 键 词：磁共振成像 T2-mapping技术 定量检测 椎间盘退变 椎间盘 腰椎 肥胖 

分 类 号：R6[医药卫生—外科学] R44[医药卫生—临床医学]