基于三氯生医用缝合线表面抗菌涂层的制备及性能  

Preparation and Performance of Triclosan-based Anti-bacterial Coatings on Medical Sutures

作　　者：童汇慧 张威迪 胡惠文 程逵[2] TONG Huihui;ZHANG Weidi;HU Huiwen;CHENG Kui(Zhejiang Gongshang University,Hangzhou 310000,China;School of Material Science and Engineering,Zhejiang University,Hangzhou 310027,China)

机构地区：[1]浙江工商大学,浙江杭州310027 [2]浙江大学材料科学与工程学院,浙江杭州310027

出　　处：《材料科学与工程学报》2019年第6期880-883,895,共5页Journal of Materials Science and Engineering

摘　　要：利用聚多巴胺可在多种不同材料的表面结合其他分子的特性,将具有杀菌作用的三氯生分子有效地固载于医用缝合线表面形成抗菌涂层。研究结果显示,涂层使表面三氯生可有效地固载于医用缝合线表面,并缓慢释放。金黄色葡萄球菌和大肠杆菌抗菌实验显示,有抗菌涂层的缝合线表面具有显著的抗菌效应。该种涂层制备方法及涂层有望广泛应用于不同类型的医用缝合线的表面作抗菌处理。In order to meet the antimicrobial requirement of medical sutures,triclosan molecules with bactericidal property was immobilized on the surface of sutures through a polydopamine method.The results showed that triclosan was effectively immobilized on the surface and could be released slowly.The antimicrobial experiments showed that the suture surface with coating had significant antimicrobial effect.Such preparation method and corresponding coating show much potential in surface modification of different types of medical sutures.

关 键 词：医用缝合线 抗菌涂层 聚多巴胺 三氯生 

分 类 号：TQ126.3[化学工程—无机化工]