18例儿童环状肉芽肿临床及组织病理分析  

Clinical and Pathological Analysis of 18 Cases of Children with Granuloma Annulare

作　　者：鲁慧[1] 钱华[1] 李巍[1] 胡翠[1] LU Hui;QIAN Hua;LI Wei(Department of dermatology,Children's hospital of Soochow university,Su Zhou,215003)

机构地区：[1]苏州大学附属儿童医院皮肤科,江苏苏州215003

出　　处：《医学临床研究》2019年第12期2305-2306,2309,共3页Journal of Clinical Research

基　　金：苏州市2016年度第十一批产业技术创新专项课题(SYS201644)。

摘　　要：【目的】探讨儿童环状肉芽肿的临床及组织病理特点。【方法】回顾性分析2013年1月至2018年12月本院皮肤科收治的18例儿童环状肉芽肿患儿的临床资料及组织病理学检查结果。【结果】皮损多表现为单一的环状红斑或由红色丘疹融合成的斑块,边界较清楚。组织病理学检查显示真皮内栅样肉芽肿性改变,中央有变性的胶原纤维,周围可见栅状排列的淋巴细胞、组织细胞以及少量多核巨细胞。【结论】根据典型的皮损特点及病理表现可诊断儿童环状肉芽肿。【Objective】To summarize the clinical and histopathological features of granuloma annularis in children.【Methods】The clinical data and histopathological findings of 18 children with granuloma annulare diagnosed and treated in children's Hospital of Soochow University from January 2013 to December 2018 were analyzed retrospectively.【Results】The skin lesions were mostly characterized by single circular erythema or plaques fused by red papules with clear boundary.Histopathological examination showed palisade granulomatous changes in the dermis with degenerated collagen fibers in the center and palisade arrangement of lymphocytes,histiocytes and a small number of epithelioid cells around the dermis.【Conclusion】According to the typical skin lesion characteristics and pathological manifestations,the diagnosis of granuloma annular can be confirmed.

关 键 词：环形肉芽肿/病理学 儿童 

分 类 号：R725.976[医药卫生—儿科]