2016-2017年四川省民族地区甲型肝炎发病危险因素病例对照研究  

A Case-control Study on Risk Factors of Hepatitis A in Minority Areas of Sichuan Province From 2016 to 2017

作　　者：刘宇[1] 刘丽珺[1] 陈筱纯[1] 刘家洁[1] 胡新[1] 包莹 杨庆 李银乔[1] LIU Yu;LIU Lijun;CHEN Xiaochun;LIU Jiajie;HU Xin;BAO Ying;YANG Qing;LI Yinqiao(Sichuan Center for Disease Prevention and Control,Chengdu 610041,Sichuan Province,China)

机构地区：[1]四川省疾病预防控制中心

出　　处：《预防医学情报杂志》2020年第2期158-161,共4页Journal of Preventive Medicine Information

摘　　要：目的探讨四川省民族地区甲肝发病的危险因素,为采取有针对性的防控措施,进一步减少甲肝发病提供依据。方法以四川省民族地区3个县发病时间为2016-01-01/2017-12-31的98例甲肝散发病例为研究对象,进行1∶1配比的病例对照研究,用条件Logistic回归模型进行单因素和多因素分析。结果四川省民族地区甲肝发病的主要危险因素为无甲肝疫苗免疫史、有甲肝患者密切接触史、居所卫生状况不清洁、生食肉类这4个因素。结论应在民族地区大力开展健康教育和健康促进,及时发现和隔离传染源,进一步做好适龄儿童甲肝疫苗的接种工作,努力提高接种及时性,积极推广成人甲肝疫苗接种,将有望减少四川省民族地区甲肝的发生。Objective To evaluate the risk factors of hepatitis A in minority areas in Sichuan province aiming to make effective measures to control and prevent the hepatitis A and provide evidences for further reducing the incidence of hepatitis A.Methods A 1∶1 case-control study was conducted.The case group included 98 sporadic hepatitis A cases in 3 counties in minority areas of Sichuan province from Jan 1st in 2016 to Dec 31 in 2017.The conditional logistic regression model was used for univariate and multivariate analysis.Results The main risk factors for hepatitis A in minority areas of Sichuan province are no hepatitis A vaccine history,close contact with hepatitis A patients,unsanitary residential environment,and eating raw meat.Conclusion Great efforts should be made to health education and health promotion.Find and isolate the infection source of hepatitis A in time,inoculate children hepatitis A vaccination in appropriate age,and generalize the adults’hepatitis A vaccination simultaneously in order to reduce the hepatitis A cases in minority areas of Sichuan province.

关 键 词：甲型肝炎 病例对照研究 危险因素 

分 类 号：R181.2[医药卫生—流行病学]