搏动性耳鸣与颞骨蜂房气化程度关系的体外实验研究  

An in vitro Experiment on Relationship Between Pulsatile Tinnitus and Temporal Bone Pneumatization Grade

作　　者：田山[1,2] 樊星雨 刘兆会[4] 王丽珍[1,2] TIAN Shan;FAN Xingyu;LIU Zhaohui;WANG Lizhen(Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education,School of Biological Science and Medical Engineering,Beijing 100083,China;Beijing Advanced Innovation Center for Biomedical Engineering,Beihang University,Beijing 100083,China;College of Bioengineering,Chongqing University,Chongqing 400044,China;Department of Radiology,Beijing Tongren Hospital,Capital Medical University,Beijing 100730,China)

机构地区：[1]北京航空航天大学生物与医学工程学院生物力学与力生物学教育部重点实验室,北京100083 [2]北京航空航天大学生物医学工程高精尖创新中心,北京100083 [3]重庆大学生物工程学院,重庆400044 [4]首都医科大学附属北京同仁医院放射科,北京100730

出　　处：《医用生物力学》2019年第6期574-579,共6页Journal of Medical Biomechanics

基　　金：国家自然科学基金项目(11421202);北京市卫生系统高层次卫生技术人才(2015-3-016)

摘　　要：目的研究搏动性耳鸣与颞骨蜂房气化程度关系。方法通过体外实验模拟乙状窦静脉声的产生、传导,并对鼓膜处接收到的声信号进行时域和时频域分析。结果骨板缺损时,所有蜂房的静脉声都有高声压、脉动性。气化一般蜂房静脉声声压最高。骨板完整时,所有蜂房的静脉声脉动性微弱,且声压接近背景声。不同气化程度蜂房接收到的静脉声脉动性频段各不相同。结论气化一般蜂房的静脉声放大效果最好,气化不足蜂房对静脉声的放大效果最差。颞骨蜂房气化程度不是导致致病静脉声的充分或必要条件。乙状窦沟骨板缺损是导致致病静脉声的充分条件。Objective To study the relationship between pulsatile tinnitus and temporal bone pneumatization grade.Methods Through the in vitro experiment,the generation and transmission pathways of the venous sound were simulated.The sound signals at the position of eardrum were recorded and analyzed.Results In case of cortical plate dehiscence,the high pressure and pulse-synchronous venous sounds were received at eardrum.The highest sound pressure occurred in the normal pneumatization case.In case of cortical plate intactness,the non-pulsatile venous sounds with pressure close to the background control sound were received at eardrum.Temporal bone air cells(TBAC)with different pneumatization grades would transmit venous sound in different frequency ranges.Conclusions Normal pneumatization TBAC exhibited the highest amplification on venous sound,while hypopneumatization TBAC exhibited the lowest amplification on venous sound.The pneumatization grade of TBAC is neither the sufficient nor essential condition of pathogenic venous sound,while the cortical plate dehiscence is the sufficient or necessary condition of pathogenic venous sound.

关 键 词：搏动性耳鸣 乙状窦骨板 颞骨蜂房 气化 体外实验 

分 类 号：R318.01[医药卫生—生物医学工程]