109例下咽后壁癌患者的治疗分析  

Analysis on the treatment of posterior pharyngeal wall carcinoma in 109 patients

作　　者：许雅 魏东敏[1] 钱晔[1] 李文明[1] 刘大昱[1] 潘新良[1] 雷大鹏[1] XU Ya;WEI Dong-min;QIAN Ye;LI Wen-ming;LIU Da-yu;PAN Xin-liang;LEI Da-peng(Department of Otorhinolaryngology,Qilu Hospital,Shandong University,Key Lab of Otolaryngology of National Health Commission,Jinan 250012,China)

机构地区：[1]山东大学齐鲁医院耳鼻咽喉科国家卫健委耳鼻喉科学重点实验室

出　　处：《中国耳鼻咽喉颅底外科杂志》2020年第1期63-66,共4页Chinese Journal of Otorhinolaryngology-skull Base Surgery

基　　金：山东省重点研发计划项目(2019GSF108003,2019GSF108097)

摘　　要：目的探讨影响下咽后壁癌患者预后的相关因素,为下咽后壁癌的治疗提供新的思路。方法收集2009年1月-2017年12月手术治疗的109例下咽后壁鳞状细胞癌患者,按照性别、是否保留喉功能、T分期、N分期、临床分期、肿瘤分化程度、手术方法及治疗方式分别分组,分析不同分组之间生存率的差别。结果下咽后壁癌患者的1、3、5年生存率分别为75%、52%、38%。下咽后壁癌N分期以及临床分期越早,生存率越高。结论只要选取了合适的手术入路保证肿瘤完整切除,可以保留患者的喉功能,并且对咽功能进行修复,从而提高患者的术后生活质量。Objective To investigate the related factors affecting the prognosis of patients with posterior pharyngeal wall carcinoma(PPWC), so as to provide new ideas for the treatment of this tumor. Methods Clinical data of 109 patients who underwent PPWC surgery in our department from Jan 2009 to Dec 2017 were collected. The survival rate differences between different groups based on patients’ gender, retaining laryngeal function, the T stage, N stage, clinical stage and pathological differentiation of tumor, surgical and treatment methods, were analyzed.Results The overall 1-year, 3-year and 5-year survival rates of the 109 patients were 75%, 52% and 38% respectively. The earlier were the N stage and clinical stage of PPWC, the higher survival rate the patients had.Conclusion As long as appropriate surgical approach is selected to ensure complete resection of PPWC, the laryngeal function of the patient can be preserved and the pharyngeal function can be repaired, which can improve the postoperative quality of life of the PPWC patients.

关 键 词：下咽后壁癌 手术 外科重建 喉功能 

分 类 号：R766.9[医药卫生—耳鼻咽喉科]