ICU重症肺炎伴呼吸衰竭患者行不同通气治疗对血气指标、心功能指标、炎性指标的影响  

Effect of different ventilation therapy on blood gas index,cardiac function index and inflammatory index in patients with severe pneumonia complicated with respiratory failure

作　　者：潘道卓 费东生[1] 杨锁柱[1] 宋文雨 PAN Daozhuo;FEI Dongsheng;YANG Suozhu;SONG Wenyu(Department of Critical Care Medicine,The First Affiliated Hospital of Harbin Medical University,Haerbin,Heilongjiang 150001,China)

机构地区：[1]哈尔滨医科大学附属第一医院重症医学科

出　　处：《国际检验医学杂志》2020年第5期629-632,共4页International Journal of Laboratory Medicine

摘　　要：目的分析探讨ICU重症肺炎伴呼吸衰竭患者行不同通气治疗对血气指标、心功能指标、炎性指标的影响。方法选择2017年6月至2018年6月期间在医院ICU病房接受治疗的60例重症肺炎伴呼吸衰竭患者作为研究对象,随机分成观察组、对照组各30例。对照组仅接受有创机械通气干预,观察组则接受有创-无创序贯通气干预。对两组患者的临床治疗情况,血气指标、心功能指标、炎性指标的变化情况以及预后情况进行比较。结果观察组患者的ICU住院时间、总住院时间均明显短于对照组患者(P<0.05);两组治疗后血气指标比较的差异无统计学意义(P>0.05);观察组治疗后心功能指标明显优于对照组(P<0.05);观察组治疗后炎性指标明显优于对照组(P<0.05);观察组患者的撤机成功率明显高于对照组患者,呼吸机相关性肺炎(VAP)发生率、病死率均明显低于对照组患者(P<0.05)。结论ICU重症肺炎伴呼吸衰竭患者行有创-无创序贯通气治疗能够获得良好临床效果,显著改善患者的血气指标、炎性指标,且对心功能的影响较少,有助于患者的预后。Objective To analyze and observe the effect of different ventilation therapy on blood gas index,cardiac function index and inflammatory index in patients with severe pneumonia complicated with respiratory failure.Methods 60 patients with severe pneumonia complicated with respiratory failure in ICU from June 2017 to June 2018 were selected as subjects,and were divided into the observation group(30 cases)and control group(30 cases).The patients of the control group were treated invasive mechanical ventilation,while the patients of the observation group were treated with invasive-noninvasive sequential ventilation.The clinical treatment,changes in blood gas index,cardiac function index,inflammatory index and prognosis between the two groups were compared.Results The ICU stay and total hospital stay in the observation group were significantly shorter than those in the control group(P<0.05).There was no significant difference in blood gas index between the two groups after treatment(P>0.05).The cardiac function index of the observation group was significantly better than that of the control group(P<0.05).The inflammatory index of the observation group was significantly better than that of the control group(P<0.05).The success rate of weaning in the observation group was significantly higher than that in the control group,and the incidence of VAP and mortality were significantly lower than those in the control group(P<0.05).Conclusion Invasive-noninvasive sequential ventilation in patients with severe pneumonia complicated with respiratory failure in ICU can achieve good clinical results,significantly improve the blood gas index and inflammatory index of patients,and have less impact on cardiac function,which is helpful to the prognosis of patients.

关 键 词：症肺炎 呼吸衰竭 有创机械通气 无创通气 效果 

分 类 号：R446.1[医药卫生—诊断学]