对新生儿病理性黄疸患儿病情临床特点的分析  

Clinical analysis of 80 cases of abnormal myocardial enzymes in neonatal pathological jaundice

作　　者：赵玉风 Zhao Yu-feng(Department of Neonatology,Fenyang Hospital Affilitated to Shanxi Medical University,Fenyang,Shanxi 032200,China)

机构地区：[1]山西医科大学附属汾阳医院新生儿科

出　　处：《当代医药论丛》2020年第1期185-186,共2页

摘　　要：目的:分析新生儿病理性黄疸患儿病情的临床特点。方法:选取2017年10月至2018年3月在山西医科大学附属汾阳医院进行治疗的120例新生儿黄疸患儿作为研究对象。将其中新生儿生理性黄疸患儿设为对照组(n=40),将其中新生儿病理性黄疸患儿设为观察组(n=80)。将观察组患儿中日龄≤7 d的患儿设为观察Ⅰ组(n=54),将观察组患儿中日龄>7 d的患儿设为观察Ⅱ组(n=26)。然后,比较这些患儿的各项临床指标。结果:观察组患儿总胆红素、乳酸脱氢酶、ɑ-羟丁酸脱氢酶、肌酸激酶及肌酸激酶同工酶的水平、其乳酸脱氢酶水平异常、ɑ-羟丁酸脱氢酶水平异常、肌酸激酶水平异常及肌酸激酶同工酶水平异常的发生率均高于对照组患儿,P<0.05;观察Ⅱ组患儿与观察Ⅰ组患儿总胆红素的水平相比,P>0.05;观察Ⅱ组患儿乳酸脱氢酶、ɑ-羟丁酸脱氢酶、肌酸激酶及肌酸激酶同工酶的水平均低于观察Ⅰ组患儿,P<0.05。结论:与新生儿生理性黄疸患儿相比,新生儿病理性黄疸患儿总胆红素、乳酸脱氢酶、ɑ-羟丁酸脱氢酶、肌酸激酶及肌酸激酶同工酶的水平均较高。与日龄>7 d的新生儿病理性黄疸患儿相比,日龄≤7 d的新生儿病理性黄疸患儿乳酸脱氢酶、ɑ-羟丁酸脱氢酶、肌酸激酶及肌酸激酶同工酶的水平均较高。Objective To explore the relationship between pathological jaundice of newborn and abnormal myocardial enzymes.Methods Eighty cases of neonatal pathological jaundice diagnosed in our hospital from October 2017 to March 2018 were selected as observation group.Forty cases of physiological jaundice in our hospital during the same period were randomly selected as control group.The bilirubin and myocardial enzymes were measured by venous blood.Results The abnormal rates of myocardal enzymes CK,CK-MB,LDH andɑ—HBDH in the observation group were higher than those in the control group,and the difference was statistically significant(P<0.05).The myocardal enzymes CK,CK-MB,LDH andɑ—HBDH in the observation group were statistically higher than those in the control group(P<0.05).Compared with late neonates,myocardal enzymes CK,CK-MB,LDH andɑ—HBDH in early neonates were significantly increased(P<0.05).Conclusion Abnormal myocardal enzymes may occur in neonatal pathological jaundice.The earlier the jaundice occurs,the more severe the jaundice is,the more obvious the increase of myocardal enzymes is.

关 键 词：新生儿病理性黄疸 新生儿生理性黄疸 临床特点 

分 类 号：R722.17[医药卫生—儿科]